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ProteomicsNetwork Analysis Reveals Age- and Virus-Specific Circuits in Nasal Epithelial Cells of Extremely Premature Infants
Viral respiratory infections significantly affect young children, particularly extremely premature infants, resulting in high hospitalization rates and increased health-care burdens. Despite posing substantial health risks, airway immune responses in early life remain largely unexplored. Nasal epith...
ORGANISM(S): Homo sapiens (Human) 
2024-11-06 | PXD042209 | Pride
Nasal epithelial cells Premature infants Virus-specific pathways 
MetabolomicsClinical features and Multiomics Profiles Indicate Coagulation and Platelet Dysfunction as Key Pathological Pathways in COVID-19 Viral Sepsis
Background: The role of viral infections as a mediator of systemic immune dysfunction leading to sepsis has received limited attention compared to the bacterial pathogens. The COVID-19 pandemic and the increased cases of sepsis in the absence of known bacterial pathogens have highlighted the clinica...
2025-12-05 | MTBLS9664 | MetaboLights
ModelsMiao2014 - Dynamics and migratory pathways of virus-specific antibody-secreting cell populations
This model is from the paper available at http://www.ncbi.nlm.nih.gov/pubmed/25171166. The original model contains time-varying parameters which are described by a smoothing spline. In this model parameters S1 and S2 are placeholders for these time-varying parameters. The model can be explored and...
2015-04-15 | MODEL1411130000 | BioModels
TranscriptomicsMiRNA profiling during infection with H7N7 influenza A virus (A/Ck/Germany/R28/H7N7/2003)
MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In c...
ORGANISM(S): Homo sapiens 
2012-04-09 | E-GEOD-36462 | biostudies-arrayexpress
TranscriptomicsMiRNA profiling during infection with H1N1 influenza A virus (A/Mexico/InDRE4487/H1N1/2009)
MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In c...
ORGANISM(S): Homo sapiens 
2012-04-09 | E-GEOD-36461 | biostudies-arrayexpress
TranscriptomicsmRNA profiling during infection with H1N1 influenza A virus (A/Mexico/InDRE4487/H1N1/2009)
MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In c...
ORGANISM(S): Homo sapiens 
2012-04-09 | E-GEOD-36553 | biostudies-arrayexpress
TranscriptomicsA Dicistrovirus-specific inducible antiviral response in Drosophila
The fruit fly Drosophila melanogaster is a good model to unravel the molecular mechanisms of innate immunity, and has led to some important discoveries on the sensing and signalling of microbial infections. The response of drosophila to virus infections remains poorly characterized, and appears to i...
ORGANISM(S): Drosophila melanogaster 
2013-02-06 | E-GEOD-31542 | biostudies-arrayexpress
ProteomicsTemporal proteomic profiling reveals functional pathways in vaccinia-induced cell migration
Viral diseases have alwanys been intricate and persistent issues throughout the world and lack of holistic discoveries of molecular dysregulations of virus-host interactions. The temporal proteomics strategy can identify various differentially expressed proteins and offer collaborated interaction ne...
ORGANISM(S): Chlorocebus sabaeus 
2023-05-04 | PXD040845 | Pride
Host-virus interactions Cell migration Regulation of actin cytoskeleton Vaccinia virus Temporal proteomics 
UnknownTransforming Growth Factor β Acts as a Regulatory Molecule for Lipogenic Pathways among Hepatitis C Virus Genotype-Specific Infections.
Not available
S-EPMC6714813 | biostudies-literature
TranscriptomicsDissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation
MLK3 gene mutations were described to occur in about 20% of microsatellite unstable gastrointestinal cancers and to harbor oncogenic activity. In particular, mutation P252H, located in the kinase domain, was found to have a strong transforming potential, and to promote the growth of highly invasive ...
ORGANISM(S): Homo sapiens 
2014-03-21 | E-GEOD-54611 | biostudies-arrayexpress
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