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MetabolomicsCadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes
Obesity is considered as a major public health concern with strong economic and social burdens. Exposure to pollutants such as heavy metals can contribute to the development of obesity and its associated metabolic disorders, including type 2 diabetes and cardiovascular diseases. Adipose tissue is an...
2023-06-29 | MTBLS4128 | MetaboLights
MetabolomicsVisceral obesity-Induced METTL27 regulation of the FABP5/PPARD/CPT1A axis in promoting colorectal cancer progression

The incidence of obesity and colorectal cancer (CRC) is rising annually. Obesity, particularly visceral obesity, poses a serious health threat, yet the association of obesity with CRC progression, as well as the role of visceral obesity, remains debated. This study analyzed 394 CRC patients ...

2025-10-06 | MTBLS13095 | MetaboLights
ProteomicsComparative proteomics of human visceral and subcutaneous adipocytes
Adipose tissue (AT) distribution is an important determinant of cardiometabolic health. Increased visceral adiposity has been associated with a higher risk of obesity-related diseases. An important step in deciphering the molecular complexity of subcutaneous AT (SAT) and visceral AT (VAT) is to eluc...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD024734 | Pride
Human Lc-msms Obesity Adipocytes Subcutaneous adipose tissue Adipose tissue Visceral adipose tissue 
TranscriptomicsExpression Data from Bone Marrow Progenitor-Derived Adipocytes, White Adipocytes and Brown Adipocytes.
We have identified a population of adipocytes in fat tissue that arise from bone marrow-derived progenitor cells. We used microarrays to compare the global gene expression patterns of the bone marrow progenitor-derived adipocytes as well as conventional white and brown adipocytes to evaluate the rel...
ORGANISM(S): Mus musculus 
2010-01-08 | E-GEOD-19757 | biostudies-arrayexpress
GenomicsDevelopmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole]
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole]
PRJNA434804 | ENA
GenomicsDevelopmental origins define epigenomic differences between subcutaneous and visceral adipocytes [microarrays]
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [microarrays]
PRJNA434428 | ENA
ProteomicsProteome analysis of human visceral and subcutaneous adipocytes identifies altered metabolic control points
Adipose tissue is a primary regulator of energy balance and metabolism. The distribution of adipose tissue depots is of clinical interest because the accumulation of upper-body subcutaneous (ASAT) and visceral adipose tissue (VAT) is associated with cardiometabolic diseases, whereas lower-body glute...
ORGANISM(S): Homo sapiens (Human) 
2021-04-19 | PXD018314 | Pride
Lipid metabolism Proteomics Swathßms Adipose tissue Obesity 
GenomicsDevelopmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq]
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq]
PRJNA434654 | ENA
GenomicsDevelopmental origins define epigenomic differences between subcutaneous and visceral adipocytes [Bisulfite-Seq]
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [Bisulfite-Seq]
PRJNA437062 | ENA
ProteomicsSARS-CoV-2 infects adipocytes in a fat depot- and viral strain-dependent manner
Visceral adiposity is a risk factor for severe COVID-19 and a link between adipose tissue infection and disease progression has been proposed. Here we demonstrate that SARS-CoV-2 undergoes productive infection in adipocytes, although the degree of infection and the cellular response depend on the an...
ORGANISM(S): Homo sapiens (Human) 
2024-02-29 | PXD030910 | Pride
Visceral adipocytes Inflammatory response Subcutaneous adipocytes Adipocytes Sars-cov-2 infection 
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