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ProteomicsEnvironmental viscosity modulates interbacterial killing during habitat transition
In this study we employed a proteomics method to determine how bacteria respond at the protein level to a transition from a low- to a high-viscosity liquid environment. We applied this method to explore how the symbiotic marine bacterium Vibrio fischeri responds to changes in environmental viscosity...
ORGANISM(S): Aliivibrio fischeri 
2020-01-07 | PXD015403 | Pride
Aliivibrio fischeri Squid-vibrio symbiosis Vibrio fischeri Symbiont 1d-lc-ms/ms Type vi secretion system 
TranscriptomicsEffect of extracellular fluid viscosity in macrophages
Extracellular fluid (ECF) viscosity as a novel and vital mechanical cue in TME. However, it remains elusive how immune cells, particularly macrophages, respond to a hyperviscous TME. Macrophages likely perceive changes in fluid viscosity as a mechanical stress at the cell membrane, which be transduc...
ORGANISM(S): Mus musculus 
2026-08-19 | GSE344008 | GEO
GenomicsCounterintuitive effect of extracellular fluid viscosity on enhancing motility and metastasis
Counterintuitive effect of extracellular fluid viscosity on enhancing motility and metastasis
PRJNA841680 | ENA
GenomicsCell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells
Cell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells
PRJEB81890 | ENA
GenomicsCampylobacter jejuni transcriptional response during growth in media with low and high viscosity
Campylobacter jejuni transcriptional response during growth in media with low and high viscosity
PRJNA1381678 | ENA
TranscriptomicsCell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells
Metastases arise from a multi-step process during which tumor cells change their mechanics in response to microenvironmental cues. While such mechanical adaptability could influence metastatic success, how tumor cell mechanics directly impacts intravascular behavior of circulating tumor cells (CTCs)...
ORGANISM(S): Mus musculus 
2024-11-24 | E-MTAB-14571 | biostudies-arrayexpress
TranscriptomicsCounterintuitive effect of extracellular fluid viscosity on enhancing motility and metastasis
Cells respond to physical stimuli, such as stiffness, fluid shear stress and hydraulic pressure. Extracellular fluid viscosity is a key physical cue that varies under physiological and pathological conditions, such as cancer. However, its impact on cancer biology and the mechanism by which cells sen...
ORGANISM(S): Homo sapiens 
2022-07-27 | GSE203651 | GEO
ProteomicsThe effect of citrate supplementation on medium viscosity and poly-γ-glutamic acid synthesis by engineered B. subtilis 168
The industrially attractive biopolymer Poly-γ-glutamic acid (γ-PGA) is commonly produced by species of the genus Bacillus by co-feeding different carbon- and nitrogen sources. Recent studies have highlighted the pivotal role of co-metabolization of a rapidly degradable carbon source such as glycerol...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2025-02-10 | PXD058048 | Pride
Vimos (viscosity monitoring online system) Γ-pga Viscosity Catabolite repression Biopolymer Bacillus subtilis Co-feed 
TranscriptomicsCampylobacter jejuni transcriptional response during growth in media with low and high viscosity
Campylobacter jejuni normally grows in the lower intestinal mucus layer as a commensal in avian and animal hosts or as a pathogen in humans. Increasing viscosity of media to physiological levels present in lower intestinal mucus has been observed to increase growth and swimming velocity of WT C. jej...
ORGANISM(S): Campylobacter jejuni 
2026-05-22 | GSE313853 | GEO
TranscriptomicsDisruption of gul-1 decreased the culture viscosity and improved protein secretion in the filamentous fungus Neurospora crassa
In this study, we screened morphological mutants in the filamentous fungus N. crassa. Of the 90 morphological mutants screened, 14 mutants exhibited considerably higher viscosity compared with that of the wild type strain, and only 2 mutants showed low-viscosity morphologies in submerged culture. We...
ORGANISM(S): Neurospora crassa 
2018-04-19 | GSE113321 | GEO
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