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MetabolomicsFunctional metabolomics as a tool to analyze Mediator function and structure in plants
Mediator is a multiprotein transcriptional co-regulator complex composed of four modules; Head, Middle, Tail, and Kinase. It conveys signals from promoter-bound transcriptional regulators to RNA polymerase II and thus plays an essential role in eukaryotic gene regulation. We describe subunit localiz...
2018-01-30 | MTBLS450 | MetaboLights
MetabolomicsUntargeted metabolomics as a hypothesis-generation tool in plant protection product discovery: Highlighting the potential of trehalose and glycerol metabolism of fungal conidiospores as novel targets

INTRODUCTION: The production of high quality and safe food represents a main priority for the agri-food sector in the effort to sustain the exponentially growing human population. Nonetheless, there are major challenges that require the discovery of new, alternative, and improved...

2020-09-08 | MTBLS1565 | MetaboLights
ProteomicsQuantification of Raloxifene Specific 471 Da Adducts in CYP3A4 and P450-Reductase
Drugs are often metabolized to reactive intermediates that form protein adducts. Adducts can inhibit critical proteins, elicit immune responses, and cause life threatening adverse drug reactions. The masses of metabolites are frequently unknown, rendering traditional mass spectrometry-based proteomi...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2022-02-21 | PXD024932 | panorama
ProteomicsTDFragMapper: Evaluating experimental parameters for confident intact protein characterization in top-down proteomics
New software-tool allowing an easy visualization of fragment ions and thus a rapid evaluation of key experimental parameters on the sequence coverage obtained for the MS/MS analysis of intact proteins. Our tool can deal with multiple fragmentation methods. We demonstrate that TDFragMapper can rapidl...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Streptococcus dysgalactiae Escherichia coli 
2021-12-30 | PXD024643 | Pride
Visualization tool Top-down proteomics Lc-ms/ms 
ProteomicsPINE: An Automation Tool to Extract & Visualize Functionally Enriched Networks from Mass Spectrometry-Based Proteomics Datasets
Recent surges in mass spectrometry-based proteomics studies demands a concurrent rise in speedy and optimized data processing tools and pipelines. While several stand-alone databases exist that store gene interaction and annotation information, we developed Protein Interaction Network Extractor (PIN...
ORGANISM(S): Mus Musculus 
2021-02-23 | PXD017324 | panorama
UnknownAn interactive visualization tool for multi-channel confocal microscopy data in neurobiology research.
Not available
S-EPMC2874972 | biostudies-literature
ProteomicsSequence Coverage Visualizer: A web application for protein sequence coverage 3D visualization
Protein structure is connected with its function and interaction and plays an extremely important role in protein characterization. As one of the most important analytical methods for protein characterization, Proteomics is widely used to determine protein composition, quantitation, interaction, and...
ORGANISM(S): Homo sapiens (Human) 
2022-12-14 | PXD032786 | Pride
Proteomics Protein sequence coverage 3d structure Visualization 
TranscriptomicsIdentification of a p-coumarate degradation regulon in Rhodopseudomonas palustris using Xpression, an integrated tool for prokaryotic RNA-seq data processing
High-throughput sequencing of cDNA prepared from RNA, an approach known as RNA-seq, is coming into increasing use as a method for transcriptome analysis. Despite its many advantages, widespread adoption of the technique has been hampered by a lack of easy-to-use, integrated, open source tools for an...
ORGANISM(S): Rhodopseudomonas palustris CGA009 
2012-09-01 | E-GEOD-39025 | biostudies-arrayexpress
UnknownABrainVis: an android brain image visualization tool.
Not available
S-EPMC8323223 | biostudies-literature
Proteomics,MultiomicsLIQUID publication data - human plasma lipids
These files are associated with the publication of the LIQUID identification tool for lipid MS/MS spectra.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-11-28 | MSV000080359 | MassIVE
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