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TranscriptomicsTranscription in wounded rat vocal folds and vocal fold fibroblasts
We used microarrays to characterize transcriptome profiles of rat vocal fold tissue following surgical injury (vs. naive tissue); rat vocal fold fibroblasts harvested from scar tissue at the 60 d time point (vs. naive fibroblasts); rat vocal fold scar fibroblasts treated with siRNA against the coll...
ORGANISM(S): Rattus norvegicus 
2014-10-09 | E-GEOD-62204 | biostudies-arrayexpress
GenomicsInjection of Vocal Fold Lamina Propria-Derived Hydrogels Modulates Fibrosis in Injured Vocal Folds
Injection of Vocal Fold Lamina Propria-Derived Hydrogels Modulates Fibrosis in Injured Vocal Folds
PRJNA1255487 | ENA
ProteomicsComparative proteomics of paired human vocal fold and oral mucosa tissue
This dataset brief is about the descriptive proteomic comparison of human oral mucosa and vocal fold tissues by high-resolution mass spectrometry (CID-MS/MS). The vast majority of voice disorders is associated with changes of the unique but delicate tissue of the human vocal folds, wheras the abili...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD025519 | Pride
Oral mucosa Comparative proteomics Human tissue Vocal folds 
GenomicsRNA-Seq of vocal folds of rabbits exposed to a low relative humidity environment
RNA-Seq of vocal folds of rabbits exposed to a low relative humidity environment
PRJNA625084 | ENA
ProteomicsProfile of Rabbit Vocal Fold Tissue Systemically Dehydrated with Furosemide
The objective of this study was to obtain a comprehensive proteome of euhydrated and systemically dehydrated rabbit vocal folds. We hypothesized that a mild-moderate systemic dehydration level would lead to changes in protein levels. New Zealand White rabbits were randomly assigned to euhydrated (c...
ORGANISM(S): Oryctolagus Cuniculus 
2020-12-17 | MSV000086612 | MassIVE
TranscriptomicsTranscription in wounded rat vocal folds and vocal fold fibroblasts
We used microarrays to characterize transcriptome profiles of rat vocal fold tissue following surgical injury (vs. naive tissue); rat vocal fold fibroblasts harvested from scar tissue at the 60 d time point (vs. naive fibroblasts); rat vocal fold scar fibroblasts treated with siRNA against the colla...
ORGANISM(S): Rattus norvegicus 
2014-10-09 | GSE62204 | GEO
ProteomicsComparative Proteomics of PairedVocal Fold and Oral Mucosa Fibroblasts
Injuries of the vocal folds frequently heal with scar formation, which can have lifelong detrimental impact on voice quality. Current treatments to prevent or resolve scars of the vocal fold mucosa are highly unsatisfactory. In contrast, the adjacent oral mucosa is mostly resistant to scarring. Thes...
ORGANISM(S): Ovis aries 
2017-01-23 | PXD005106 | Pride
Lamina propria Oral mucosa Wound healing Fibrosis Laryngology Scar Vocal folds Fibroblasts 
TranscriptomicsRNA-Seq of vocal folds of rabbits exposed to a low relative humidity environment
The purpose of this study is to investigate if acute mucosal dehydration as a funcition of low relative humidty environment impacts the vocal folds at the mRNA level. Rabbits were used as animal model to enable a systematic and rigorous assessment of the pathobiology of vocal fold hydration since th...
ORGANISM(S): Oryctolagus cuniculus 
2020-12-21 | GSE148588 | GEO
UnknownTwin vocal folds as a novel evolutionary adaptation for vocal communications in lemurs.
Not available
S-EPMC10864409 | biostudies-literature
TranscriptomicsInjection of Vocal Fold Lamina Propria-Derived Hydrogels Modulates Fibrosis in Injured Vocal Folds
Vocal fold (VF) fibrosis, often caused by phonosurgery, radiation, or trauma, leads to irreversible voice dysfunction due to excessive ECM deposition and increased tissue stiffness. VF fibrosis, a significant cause of chronic dysphonia, lacks FDA-approved treatments, highlighting the critical need f...
ORGANISM(S): Oryctolagus cuniculus 
2025-07-29 | GSE295627 | GEO
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