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ProteomicsFast and robust proteome screening platform identifies neutrophil extracellular trap formation in the lung in response to cobalt ferrite nanoparticles
The goal of this study was to investigate the effects of magnetic iron cobalt oxide nanoparticles (cobalt doped Fe3O4 nanoparticles with increasing amounts of cobalt) after pulmonary exposure while in parallel presenting a proteomics platform that is easily transferable to large-scale nanotoxicology...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-26 | PXD016148 | Pride
Tmt Iron cobalt oxide nanoparticles Balf Lung Clinical proteomics Nanoparticles Mouse Murine Label-free Metal oxide nanoparticles Bronchoalveolar lavage fluid 
UnknownMaternal bile acid transporter deficiency promotes neonatal demise.
Not available
S-EPMC4598356 | biostudies-literature
TranscriptomicsThe Histone H2B Monoubiquitination Regulatory Pathway is Required for Differentiation of Multipotent Stem Cells
Extensive changes in post-translational histone modifications accompany the rewiring of the transcriptional program during stem cell differentiation. However, the mechanisms controlling the changes in specific chromatin modifications and their function during differentiation remain only poorly under...
ORGANISM(S): Homo sapiens 
2013-01-03 | E-GEOD-38173 | biostudies-arrayexpress
Genomicsena-DATASET-UCL-ICH-25-11-2015-12:32:35:398-26 - samples
Description not provided
EGAD00001001687 | EGA
GenomicsTelomerase activation by genomic rearrangements in high-risk neuroblastoma
Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system1. Roughly half of these tumors regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavorable clinical course despite intensive multimodal treatment, and their molecular b...
EGAS00001001308 | EGA
GenomicsDAC University Hospital Cologne
Data Access Committee EGAC00001000361
EGAC00001000361 | EGA
UnknownComparison of Group-Level and Individualized Brain Regions for Measuring Change in Longitudinal Tau Positron Emission Tomography in Alzheimer Disease.
Not available
S-EPMC10167602 | biostudies-literature
UnknownComparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma.
Not available
S-EPMC5506390 | biostudies-literature
ProteomicsMitochondrial damage drives T-cell immunometabolic paralysis after major surgery
Cytotoxic T cell (CTL) dysfunction is a key feature of immune paralysis following major surgery, significantly increasing the risk of severe nosocomial infections and contributing to elevated mortality in critically ill patients. The pathomechanisms of CTL dysfunction remain unclear. We report that ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-02-04 | MSV000097035 | MassIVE
ProteomicsHB digestion with Pepsin and Napsin
HB digestion with Pepsin and Napsin t=20, 60 and 120 min Analysis by nanoLC-ESI-iTRAP-OrbiTrap
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-10 | MSV000087400 | MassIVE
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