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TranscriptomicsCD98 marks a subpopulation of head and neck squamous cell carcinoma cells with stem cell properties
The application of compounds specifically targeting the cancer stem cells (CSCs), in addition to routinely used therapeutics, would likely improve the clinical outcome of head and neck squamous cell carcinoma (HNSCC). The previously described monoclonal antibody K984 (now found to recognize CD98) wa...
ORGANISM(S): Homo sapiens 
2015-01-24 | E-GEOD-35477 | biostudies-arrayexpress
TranscriptomicsRNAseq of PRMT4KD in human cord blood derived CD34+ cells
Defining the role of epigenetic regulators in normal hematopoiesis has become critically important, as recurrent mutations or aberrant expression of these genes has been identified in both myeloid and lymphoid hematological malignancies. We have found that PRMT4, a type I arginine methyltransferase,...
ORGANISM(S): Homo sapiens 
2013-12-19 | E-GEOD-46056 | biostudies-arrayexpress
no omics definedTranscription profiling of Medicago truncatula radicles incubated in polyethylene glycol solution and embryos at different time points after pollination to study dessication tolerance
Time course of the transcriptome of desiccation-sensitive 2.7-2.9 mm-long radicles of Medicago truncatula seeds at different time points during incubation in a polyethylene glycol (PEG) solution at -1.7 MPa and 10°C, resulting in a gradual re-establishment of desiccation tolerance. Gene profiling wa...
ORGANISM(S): Medicago truncatula 
2006-04-30 | E-MEXP-664 | biostudies-arrayexpress
UnknownAdditional genetic alterations in BRAF-mutant gliomas correlate with histologic diagnoses.
Not available
S-EPMC7642042 | biostudies-literature
UnknownEffect of Honokiol on culture time and survival of Alzheimer's disease iPSC-derived neurons.
Not available
S-EPMC10844589 | biostudies-literature
TranscriptomicsTranscription profiling of rat peritoneal mesotheliomas following treatment with o-nitrotoluene or bromochloracetic acid
This study was performed to characterize the gene expression profile of rat peritoneal mesothelioma (RPM) formation following treatment of Fischer 344 rats with o-nitrotoluene (o-NT) or bromochloracetic acid (BCA). Experiment Overall Design: Four mesotheliomas from o-NT-treated rats and four mesot...
ORGANISM(S): Rattus norvegicus 
2008-05-07 | E-GEOD-4682 | biostudies-arrayexpress
UnknownCrystal structure of potassium hydrogen bis-((E)-2-{4-[3-(thio-phen-3-yl)acrylo-yl]phen-oxy}acetate).
Not available
S-EPMC8183452 | biostudies-literature
UnknownSpecific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis.
Not available
S-EPMC11436933 | biostudies-literature
TranscriptomicsGenome-wide expression study of the responses of murine NK cells and dendritic cell subsets to MCMV infection
Murine Cytomegalovirus (MCMV) infection leads to the activation of various immune cells, including dendritic cells (DCs) and Natural Killer (NK) cells. This activation is partly driven by innate cytokines including IFN-I, which are induced early after infection. The objective was to address the role...
ORGANISM(S): Mus musculus 
2012-10-17 | E-GEOD-39555 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression study of the early/innate responses of murine B and T cells to MCMV infection
Murine Cytomegalovirus (MCMV) infection leads to early activation of various immune cells, including B and T lymphocytes, before the actual initiation of antigen-specific adaptive immunity. This activation is partly driven by innate cytokines, including type I interferon (IFN), which are induced ear...
ORGANISM(S): Mus musculus 
2013-04-03 | E-GEOD-45365 | biostudies-arrayexpress
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