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TranscriptomicsTranscription profiling of human mesenchymal stem cells to determine changes over the course of cellular aging
To determine gene expression changes during in vitro senescence of MSC we have analyzed differential expression of the corresponding early passage (P2) and senescent passage (PX). There were global changes in the gene expression profile that were reproducible in three independent donor samples. Expe...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-9593 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adherent and non-adherent human hematopoietic progenitor cells
Comparison of gene expression of the adherent and non-adherent fraction of hematopoietic progenitor cells.
ORGANISM(S): Homo sapiens 
2007-03-13 | E-MEXP-586 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of CD34+CD38- vs CD34+CD38+ fractions of human umbilical cord blood and comparison of slow-dividing fraction vs the fast dividing fraction of CD34+/CD38- population
Comparison of the CD34+CD38- versus CD34+CD38+ fractions of human umbilical cord blood and comparison of the slow-dividing fraction versus the fast dividing fraction of the CD34+/CD38- population.
ORGANISM(S): Homo sapiens 
2005-09-08 | E-EMBL-1 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Mesenchymal Stem Cells (MSC) vs reference RNA of non-multipotent human fibroblasts HS68
Mesenchymal stem cells (MSC) resemble a multipotent adult stem cell population capable of differentiation into a number of different mesodermal cell types including adipodytes, osteoblasts, chondroblasts. Although still in debate there is some evidence, that these cells can also differentiate into c...
ORGANISM(S): Homo sapiens 
2005-08-23 | E-EMBL-4 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human gene expression profiles of CD34+/CD38- cells vs AFT024
It is widely accepted that hematopoietic progenitor cells (HPC) are tightly associated with discrete niches within the bone marrow. This molecular environment supports and regulates their self renewal and differentiation. AFT024 is a cell line derived from murine fetal liver that has been demonstrat...
ORGANISM(S): Mus musculus 
2005-06-13 | E-EMBL-3 | biostudies-arrayexpress
TranscriptomicsIn vitro Expansion of Hematopoietic Stem and Progenitor Cells Induces Tightly Regulated DNA-Hypermethylation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-40800 | biostudies-arrayexpress
GenomicsReplicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-03-26 | E-GEOD-59979 | biostudies-arrayexpress
TranscriptomicsMatrix Elasticity Does Not Affect Replicative Senescence or DNA Methylation Patterns of Mesenchymal Stem Cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-55889 | biostudies-arrayexpress
TranscriptomicsSurface topography enhances differentiation of mesenchymal stem cells towards osteogenic and adipogenic lineages
Surface topography impacts on cell growth and differentiation, but it is not trivial to generate defined surface structures and to assess the relevance of specific topographic parameters. In this study, we have systematically compared in vitro differentiation of mesenchymal stem cells (MSCs) on a va...
ORGANISM(S): Homo sapiens 
2018-09-20 | E-MTAB-7177 | biostudies-arrayexpress
TranscriptomicsSurface topography guides morphology and spatial patterning of induced pluripotent stem cell colonies
The relevance of topographic cues for commitment of induced pluripotent stem cells (iPSCs) is largely unknown. In this study, we demonstrate that groove-ridge structures with a periodicity in the submicrometer range induce elongation of iPSC colonies, guide the orientation of apical actin fibers, an...
ORGANISM(S): Homo sapiens 
2018-10-31 | E-MTAB-7327 | biostudies-arrayexpress
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