Sort   by:  
 Page size 
ProteomicsSmoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Subunits
The Hedgehog (Hh) pathway is essential for tissue homeostasis, and misregulation of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) activates glioma-associated (GLI) transcription factors via an unknown mechan...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-25 | PXD019346 | Pride
Smoothened Phosphorylation 
UnknownHIV/HCV therapy with ledipasvir/sofosbuvir after randomized switch to emtricitabine-tenofovir alafenamide-based single-tablet regimens.
Not available
S-EPMC6988963 | biostudies-literature
UnknownA single-cell atlas of RNA alternative splicing in the glioma-immune ecosystem.
Not available
S-EPMC12699894 | biostudies-literature
UnknownA Single-Cell Atlas of RNA Alternative Splicing in the Glioma-Immune Ecosystem.
Not available
S-EPMC11974875 | biostudies-literature
ProteomicsSmoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) activates glioma-associated (GLI) transcription facto...
ORGANISM(S): Homo Sapiens 
PXD023893 | panorama
TranscriptomicsBiomphalaria glabrata haemocytes vs ESPs
During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host. Following invasion of the snail, the parasite develops from a miracidium to...
ORGANISM(S): Biomphalaria glabrata 
2014-12-31 | E-MTAB-2135 | biostudies-arrayexpress
UnknownRNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma.
Not available
S-EPMC11142752 | biostudies-literature
TranscriptomicsInvestigation of placental DNA methylation in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2018-11-01 | E-MTAB-6421 | biostudies-arrayexpress
TranscriptomicsInvestigation of placental gene expression in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2019-01-31 | E-MTAB-6418 | biostudies-arrayexpress
UnknownPragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solution in open fractures (Aqueous-PREP): the feasibility of a cluster randomized crossover study.
Not available
S-EPMC7919062 | biostudies-literature
Sort   by:  
 Page size