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UnknownPrediction of early death after induction therapy for newly diagnosed acute myeloid leukemia with pretreatment risk scores: a novel paradigm for treatment assignment.
Not available
S-EPMC3221524 | biostudies-literature
UnknownFrequency of allogeneic hematopoietic cell transplantation among patients with high- or intermediate-risk acute myeloid leukemia in first complete remission.
Not available
S-EPMC3805928 | biostudies-literature
ProteomicsArginine and lysine methylproteomes of Giardia duodenalis
Methylation is a common post-translational modification of lysine and arginine in eukaryotic proteins. To date, these methylomes are best characterised in model organisms and higher eukaryotes. Herein, we integrated bioinformatics, proteomics and high-content drug-screening to comprehensively explor...
ORGANISM(S): Giardia lamblia ATCC 50803 
2020-08-07 | PXD016813 | Pride
Methylation Arginine methylation Ptm Giardia Lysine methylation 
ProteomicsActivin A and NK cell function
Natural killer (NK) cells are innate lymphocytes that play a major role in immunosurveillance against tumor initiation and metastasis spread. Signals and checkpoints that regulate NK cell fitness and function in the tumor microenvironment are not well defined. Transforming grow factor (TGF)- is a re...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-06 | PXD011672 | Pride
Activin signaling Qtof Label-free proteomics Tgf-b signaling 
TranscriptomicsHuman bronchial epithelial cells_Passage 3 vs. passage 0
Squamous metaplasia is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary disease (COPD). A major mechanism of airway obstruction in COPD is thickening of the small airway walls. We asked whether squamous metaplasia actively contributes to airway wall thicke...
ORGANISM(S): Homo sapiens 
2007-08-30 | E-GEOD-7557 | biostudies-arrayexpress
UnknownCD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.
Not available
S-EPMC5549451 | biostudies-literature
UnknownWaveband specific transcriptional control of select genetic pathways in vertebrate skin (Xiphophorus maculatus).
Not available
S-EPMC5946439 | biostudies-literature
ProteomicsTitle: Non-canonical functions of SNAIL drive context-specific progression
SNAIL is a key transcriptional regulator in embryonic development and cancer. Its effects in physiology and disease are believed to be linked to its role as a master regulator of epithelial-to-mesenchymal transition (EMT). Here, we report EMT-independent oncogenic SNAIL functions in cancer. Using ge...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-13 | PXD038726 | Pride
Transcription Emt Tissue specificity Snail Cell cycle : cancer Chip-ms 
TranscriptomicsNAC, Tiron and Trolox impair GBM tumorigenic cell survival by mechanisms independent from antioxidant activity
The aim of this study is to determine if, using antioxidant drugs, it is possible to interfere with the proliferative capabilities of the human glioblastoma (GBM) tumor-initiating cells (TICs). To establish which cellular processes are activated in GBM TICs by the antioxidants NAC, Tiron and Trolox,...
ORGANISM(S): Homo sapiens 
2014-03-04 | E-GEOD-44099 | biostudies-arrayexpress
UnknownImpaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death.
Not available
S-EPMC8212515 | biostudies-literature
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