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ProteomicsChIP-MS reveals the local chromatin composition by label-free quantitative proteomics
Chromatin immunoprecipitation (ChIP) has been a cornerstone for epigenetic analyses over the last decades, but even coupled to sequencing approaches (ChIP-seq), it is ultimately limited to one protein at a time. In a complementary effort, we here combined ChIP with label-free quantitative (LFQ) mass...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-03-05 | PXD039627 | Pride
Chip-ms Dcas9 Telomeres Lfq Myb 
GenomicsMultiple Sclerosis Replication Chip data (MS Chip)
Genetic data typed with the MS Chip, designed by the International Multiple Sclerosis Genetics Consortium (IMSGC).
EGAS00001003216 | EGA
ProteomicsChIP-MS reveals the local chromatin composition by label-free quantitative proteomics
Chromatin immunoprecipitation (ChIP) has been a cornerstone for epigenetic analyses over the last decades, but even coupled to sequencing approaches (ChIP-seq), it is ultimately limited to one protein at a time. In a complementary effort, we here combined ChIP with label-free quantitative (LFQ) mass...
ORGANISM(S): Homo sapiens (Human) 
2024-03-05 | PXD039701 | Pride
Chip-ms Telomeres Lfq 
ProteomicsQuantitative ChIP-MS analysis of proteins associated with H3K4me1- and H3K4me3-enriched mono-nucleosomes purified from crosslinked IMR-90 cells
Here we used ChIP-MS to quantitatively profile chromatin-associated proteins that are specifically associated with H3K4me1- and H3K4me3-modified nucleosomes in IMR-90 chromatin.
ORGANISM(S): Homo sapiens (Human) 
2023-12-10 | PXD042826 | Pride
H3k4me3 H3k4me1 Chip-ms 
ProteomicsHDX-MS of CHIP wt and K30A mutant
HDX-MS was used to establish that conformational-inhibition-signals extended from the TPR-domain to the U-box of CHIP. This underscores inter-domain allosteric regulation of CHIP by the core molecular chaperones. Defining the chaperone-associated TPR-domain of CHIP as a manager of inter-domain commu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-07-30 | MSV000079205 | MassIVE
ProteomicsQuantitative ChIP-MS analysis of histone modifications present on H3K4me1- and H3K4me3-enriched mono-nucleosomes purified from crosslinked IMR-90 cells
The INO80 complex is a chromatin remodeler that regulates DNA replication, repair, and transcription. Although the INO80 complex plays a crucial role in various chromatin-associated processes, the mechanism of its recruitment to specific genomic loci is not well understood. Here we used a native ChI...
ORGANISM(S): Homo sapiens (Human) 
2023-12-12 | PXD042224 | Pride
H3k4me3 H3k4me1 Histone ptms Chip-ms 
ProteomicsMultiphasic chip performance characterization using human thyroid cancer cell line SW1736 and human plasma
Development of an online peptide fractionation system comprising a multiphasic LC chip that integrates reversed phase and strong cation exchange chromatography upstream of the MS based on the multi-dimensional protein identification technology (mudPIT). Chips were assessed in terms of chromatographi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081545 | MassIVE
ProteomicsCHIP controls the expression of the neuropeptide precursor protein VGF
CHIP is a neuroprotective E3-ubiquitin ligase that supports longevity and healthy ageing. Loss of CHIP function has a major impact on life expectancy in animal models, whilst in humans’ mutations that compromise the E3-ligase activity of CHIP are causative for forms of Spinocerebellar Ataxia (SCA) t...
ORGANISM(S): Homo sapiens (Human) 
2021-07-29 | PXD016299 | Pride
Human Swath Neuropeptide Pulse silac Chip Lc-ms/ms 
UnknownImproved liquid chromatography-MS/MS of heparan sulfate oligosaccharides via chip-based pulsed makeup flow.
Not available
S-EPMC3205275 | biostudies-literature
UnknownModular Chip-Based nanoSFC-MS for Ultrafast Separations.
Not available
S-EPMC11359387 | biostudies-literature
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