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ProteomicsIdentification of H3 Lysine 4 Monomethylation Associated Proteins at Mammalian Enhancers
Enhancers act to regulate cell type specific gene expression by facilitating the transcription of target genes. In mammalian cells active or primed enhancers are commonly marked by monomethylation of Histone H3 at lysine 4 (H3K4me1) in a cell-type specific manner. Whether and how this histone modifi...
ORGANISM(S): Homo sapiens (Human) 
2018-10-23 | PXD007942 | Pride
And enhancers Monomethylation of histone h3 at lysine 4 (h3k4me1) Baf 
ProteomicsH3K4me1 directs H3K36me2 and H3K36me3 deposition in land plants
Monomethylation of histone H3 lysine 4 (H3K4me1) marks enhancers in mammals. However, the function of H3K4me1 in plants remains largely unclear. Here, we analyzed the genome-wide distribution of H3K4me1 in diverse species across evolution, revealing a distinctive H3K4me1 distribution pattern in land...
ORGANISM(S): Oryza Sativa 
2025-09-23 | PXD068723 |
GenomicsGlobal Mapping of H3K4me1 and H3K4me3 in human CD4+CD25+FOXP3+ Treg cells
Regulatory T cells (Treg) contribute to the crucial immunological processes of self-tolerance and immune homeostasis. However, the mechanisms underlying Treg function and cell fate decisions to differentiate between Treg and conventional T cells (Tconv) remain to be fully elucidated, especially at t...
ORGANISM(S): Homo sapiens 
2011-01-31 | E-GEOD-26427 | biostudies-arrayexpress
ProteomicsQuantitative ChIP-MS analysis of proteins associated with H3K4me1- and H3K4me3-enriched mono-nucleosomes purified from crosslinked IMR-90 cells
Here we used ChIP-MS to quantitatively profile chromatin-associated proteins that are specifically associated with H3K4me1- and H3K4me3-modified nucleosomes in IMR-90 chromatin.
ORGANISM(S): Homo sapiens (Human) 
2023-12-10 | PXD042826 | Pride
H3k4me3 H3k4me1 Chip-ms 
GenomicsH3K27Ac and H3K4me1 ChIP-seq in Rex1GFPd2 mouse embryonic stem cell line
Chromatin immunoprecipitation using H3K27Ac and H3K4me1 antibodies in Rex1GFPd2 mouse ES cells (parental line; E14Tg2a)
ORGANISM(S): Mus musculus 
2014-06-24 | E-MTAB-2282 | biostudies-arrayexpress
GenomicsChIP-seq for EP300 and H3K4me1 in the mouse melanocyte cell line melan-a
Using ChIP-seq for p300 and H3K4me1, we identified 2,489 putative melanocyte enhancer loci in the mouse genome. We demonstrated that these putative enhancers are evolutionarily constrained, enriched for sequence motifs predicted to bind key melanocyte transcription factors, located near genes releva...
ORGANISM(S): Mus musculus 
2012-09-14 | E-GEOD-38498 | biostudies-arrayexpress
TranscriptomicsH3K4me1 ChIP-seq of untreated HeLa S3 cells
We used ATLAS-seq to map the sites of integration of an engineered LINE-1 (L1) retrotransposon into the genome of HeLa S3 cells. Then, we compared the position of these sites with publicly available genomic datasets. In order to cross-corroborate our findings with datasets obtained in the same cell ...
ORGANISM(S): Homo sapiens 
2019-04-04 | E-MTAB-7643 | biostudies-arrayexpress
GenomicsGenome-wide identification of putative cis-regulatory elements through epigenetic profiling in zebrafish
In this study, we have applied ChIP-Seq to identify putative regulatory elements throughout the zebrafish genome. For this purpose we identified sequences within the zebrafish genome that associate with H3K4me1 and H3K4me3, which are epigenetic modifications known to be associated with active cis-r...
ORGANISM(S): Danio rerio 
2011-02-25 | E-GEOD-20600 | biostudies-arrayexpress
GenomicsH3K4me1 and H3K27ac in Vcap cells
H3K4me1 and H3K27ac in Vcap cells
PRJNA956498 | ENA
GenomicsH3K4me1 ChIP-seq of mouse small intestinal epithelium at different development stages (E18.5, P7, P21)
To assess the role of H3K4me1 in development in mouse small intestinal epithelium, we isolated intestinal epithelium tissue from wild type mice at E18.5, P7 and P21. This tissue was digested to single cells, sorted, fixed, isolated chromatin, and performed ChIP using an H3K4me1 antibody as described...
ORGANISM(S): Mus musculus 
2020-11-16 | E-MTAB-8710 | biostudies-arrayexpress
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