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UnknownMagnetic resonance imaging using a nonuniform Bo (NuBo) field-cycling magnet.
Not available
S-EPMC10270621 | biostudies-literature
ProteomicsInhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy-qualitative proteomic
The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogues as a novel chemotype inhibiting the interactions of ribosome assembly factor Mrt4 with ...
ORGANISM(S): Candida albicans (Yeast) 
2026-04-27 | PXD073550 | Pride
Ribosome assembly factor Azole-resistant fungi Protein-rna interaction Fumaramidmycin-based derivatives Target identification 
TranscriptomicsTaf7l Modulates Brown Adipose Tissue Formation
Brown adipose tissue (BAT) plays an essential role in metabolic homeostasis by dissipating energy via thermogenesis through uncoupling protein 1 (Ucp1). Previously, we reported that the TATA-binding protein Associated Factor 7L (Taf7l) is an important regulator of white adipose tissue (WAT) differen...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-55797 | biostudies-arrayexpress
UnknownAssessing the quality of reports about randomized controlled trials of acupuncture treatment on Diabetic Peripheral Neuropathy.
Not available
S-EPMC3388075 | biostudies-literature
ProteomicsInhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy
The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogues as a novel chemotype inhibiting the interactions of ribosome assembly factor Mrt4 with ...
ORGANISM(S): Candida albicans (Yeast) 
2026-04-27 | PXD068797 | Pride
Invasive fungal infections Protein-rna interaction covalent inhibitors Fumaramidmycin derivatives Ribosome assembly factor mrt4 Antifungal target identification 
ProteomicsSNC1 phosphorylation sites invivo LC-MSMS
Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060129 | Pride
Lc-msms Snc1 
ProteomicsCPK3 phosphorylates SNC1-TIR LC-MSMS
Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060014 | Pride
Lc-msms Cpk3 Snc1-tir 
UnknownCombining Hypo-Reflective Structural En Face Imaging Improves Polypoidal Lesion Detection on Spectral-Domain OCT Angiography.
Not available
S-EPMC12338367 | biostudies-literature
Transcriptomicsset2 buratowski lab
H3K36 methylation by Set2 targets Rpd3S histone deacetylase to 3’ transcribed regions, repressing internal cryptic promoters and slowing elongation. To further explore the function of this pathway, global transcription was analyzed in yeast experiencing a series of carbon source shifts. Many pr...
ORGANISM(S): Saccharomyces cerevisiae 
2016-09-25 | E-MTAB-4268 | biostudies-arrayexpress
TranscriptomicsGene expression data from mouse ES cell-derived primitive NSCs and definitive NSCs
Primitive neural stem cells (NSCs) could be derived from pluripotent mouse embryonic stem (ES) cells, and then differentiate into definitive-type neural stem cells which resemble NSCs obtained from the central nervous system. Hence, primitive NSCs define an early stage of neural induction and provid...
ORGANISM(S): Mus musculus 
2014-03-01 | E-GEOD-44608 | biostudies-arrayexpress
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