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UnknownLinked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B.
Not available
S-EPMC4515841 | biostudies-literature
UnknownNIR-activatable nitric oxide generator based on nanoparticles loaded small-molecule photosensitizers for synergetic photodynamic/gas therapy.
Not available
S-EPMC11446090 | biostudies-literature
ProteomicsRepression of PRMT5-mediated dimethylation stabilizes vimentin and promotes metastasis in MTAP-loss lung cancer
Abstract The aggressive nature and poor prognosis of lung cancer led us to explore the mechanisms driving disease progression. Utilizing our invasive cell-based model, we identified methylthioadenosine phosphorylase (MTAP) and confirmed its suppressive effects on tumorigenesis and metastasis, and pa...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD031192 | Pride
Human Dimethylation Lung cancer 
UnknownData for outcomes of acute hospital administration of amiodarone and/or lidocaine in shockable patients presenting with out-of-hospital cardiac arrest.
Not available
S-EPMC5137177 | biostudies-literature
UnknownNeoadjuvant sintilimab plus chemotherapy for locally advanced resectable esophageal squamous cell carcinoma: a prospective, single-arm, phase II clinical trial (CY-NICE).
Not available
S-EPMC10797361 | biostudies-literature
ProteomicsIdentification of CTPS1 Filament Interacting Proteins_2019 dataset
CTP synthase (CTPS) catalyzes the formation of CTP in de novo pyrimidine biosynthesis pathway. Compartmentalization of CTPS into filamentous structure is evolutionarily conserved from E.coli, yeast, Drosophila, mice to humans. Previously, we demonstrated that histidine (His) mediated methylation pro...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD015507 | Pride
Apex2 Tmt6 labeling Ctps1 Lc-ms/ms 
ProteomicsIdentification of CTPS1 Filament Interacting Proteins
CTP synthase (CTPS) catalyzes the formation of CTP in de novo pyrimidine biosynthesis pathway. Compartmentalization of CTPS into filamentous structure is evolutionarily conserved from E.coli, yeast, Drosophila, mice to humans. Recently, we have demonstrated that histidine-mediated protein methylatio...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD010921 | Pride
Snap29 Apex2 Ctps Cytokeratin 
ProteomicsQuantitative proteomics reveals inflammatory signaling in golgin-97 knockout-mediated breast cancer progression
The Golgi apparatus serves as a central hub for trafficking, regulating the anterograde transport and modification of proteins and lipids, or recycling extracellular proteins via retrograde transport through endosomes. Several Golgi-localized proteins have been reported to be involved in regulating ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD056499 | Pride
Breast cancer Golgin-97 Inflammatory Golgi Metastasis 
TranscriptomicsTranscriptome study in rhesus monkey
Rhesus Monkey is one of the important primate models widely used in the fields of disease mechanism study, pre-clinical test in drug discovery and molecular evolution. However, the majority of rhesus gene annotations were putatively mapped from human genome, with only 10% supported by rhesus EST dat...
ORGANISM(S): Macaca mulatta 
2012-10-10 | E-GEOD-34426 | biostudies-arrayexpress
TranscriptomicsHost and pathogen interaction: time course [C. albicans]
The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fis...
ORGANISM(S): Candida albicans 
2013-08-26 | E-GEOD-32117 | biostudies-arrayexpress
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