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MetabolomicsEvolutionary novelty of Apolipoprotein D facilitates metabolic plasticity in lepidopteran wing

Understanding metabolic plasticity of animal evolution is a fundamental challenge in evolutionary biology. Owing to the diversification of insect wing morphology and dynamic energy requirements, the molecular adaptation mechanisms underlying the metabolic pathways in wing evolution remain largely...

2026-03-29 | MTBLS4308 | MetaboLights
MetabolomicsEvolutionary novelty of Apolipoprotein D facilitates metabolic plasticity in lepidopteran wings

Understanding metabolic plasticity of animal evolution is a fundamental challenge in evolutionary biology. Owing to the diversification of insect wing morphology and dynamic energy requirements, the molecular adaptation mechanisms underlying the metabolic pathways in wing evolution remain largely...

2026-03-29 | MTBLS11285 | MetaboLights
MetabolomicsMetabolomics to elucidate the effects of novel sustainable feed additives in the feed of farmed salmon (HoloFood Trial D - fermented seaweed open water-dose response)

Testing the effect of seaweed as a novel cost-efficient feed source for Atlantic salmon feed. Fermentation of novel raw materials for fish feed is a new practice with little prior experience of direct relevance to aquaculture and fish farming. In Trial D, an alternative marine compound is include...

2023-06-13 | MTBLS6733 | MetaboLights
ProteomicsInteractomes of Macrophage migration inhibitory factor (MIF) and its homologue D-dopachrome tautomerase (D-DT )
NIH 3T3 fibroblasts that express little detectable levels of the MIF binding receptor CD74 but do express the signalling component CD44 were used for the identification of interacting proteins that are shared by MIF and D-DT. Endogenously expressed MIF and D-DT were tagged at the C-terminus using a ...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-27 | PXD020449 | Pride
Interactome Mif D-dt Nih 3t3 
TranscriptomicsSubtractive Hybridization Reveals Novel Genes Associated with D. melanogaster Early Embryogenesis.
Background: The early stages of D. melanogaster embryogenesis involve cell migration and pattern formation, and lead to the formation of three germ layers (the ectoderm, mesoderm and endoderm). These developmental events are controlled by differential gene activity. In the current study we used a su...
ORGANISM(S): Drosophila melanogaster 
2010-05-16 | E-GEOD-15000 | biostudies-arrayexpress
ProteomicsMycobacterium tuberculosis produces D-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice
Interferon (IFN)-γ-producing CD8+ T cells are involved in control of Mycobacterium tuberculosis (Mtb) infection, in part by promoting antimicrobial activities of macrophages. Whether Mtb counters these responses, particularly during the hypoxic conditions that arise within granulomas during infectio...
ORGANISM(S): Mycobacterium tuberculosis OFXR-32 
2024-08-10 | PXD050258 | Pride
Mycobacterium tuberculosis  d-serine  rv0884c  wdr24  mtorc1  cd8+ t cell 
ProteomicsIDH1-mutant metabolite D-2-Hydroxyglutarate inhibits proliferation and sensitizes glioma to Temozolomide via down-regulating ITGB4/PI3K/AKT
The effects of D-2HG on U251 cells by conducting a proteomic analysis
ORGANISM(S): Homo Sapiens 
PXD052264 |
MetabolomicsExperimental and computational approaches for deep metabolome annotation with application to the ecotoxicological model organism Daphnia magna

Identifying metabolomes with greater coverage and confidence is a critical step towards interpreting the metabolic basis of human and environmental health. Yet for over two decades the field of metabolomics has been inhibited by limited metabolite identification. To address this, we developed the...

MTBLS2273 | MetaboLights
GenomicsFetal hematopoietic stem cells subjected to vitamin D deficiency in utero, conferred permanent insulin resistance to vitamin D-sufficient mice
Fetal hematopoietic stem cells subjected to vitamin D deficiency in utero, conferred permanent insulin resistance to vitamin D-sufficient mice
PRJNA660424 | ENA
ProteomicsSynergistic Therapeutic Effects of D-Mannitol-Cerium-Quercetin (Rutin) Coordination Polymer Nanoparticles on Acute Lung Injury
In our latest study, we pioneered the use of D-Mannitol-Cerium-Quercetin/Rutin coordination polymer nanoparticles (MCQ/R NPs) as a potential remedy for ALI. our in vivo studies with LPS-induced ALI mice showed significant mitigation of lung tissue inflammation. This groundbreaking research presents ...
ORGANISM(S): Mus Musculus 
PXD051350 |
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