Sort   by:  
 Page size 
MetabolomicsDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...
2021-10-06 | MTBLS1503 | MetaboLights
UnknownRNA profile of control and nicotine treated Murine Leydig single cell represented in TPM data.
Not available
S-EPMC6454091 | biostudies-literature
UnknownEngineering Bacterial Biofilm Development and Structure via Regulation of Silver Nanoparticle Density in Graphene Oxide Composite Coating.
Not available
S-EPMC10900484 | biostudies-literature
UnknownRecent advances in the delivery of disulfiram: a critical analysis of promising approaches to improve its pharmacokinetic profile and anticancer efficacy.
Not available
S-EPMC6895293 | biostudies-literature
ProteomicsIdentification of SNHG9-binding proteins in Huh7 cells using RNA pull-down assay
This project aims to identify the specific proteins interacting with lncRNA SNHG9 in hepatoma cells. We performed RNA pull-down assays using biotin-labeled SNHG9 probes in Huh7 cell lysates, followed by mass spectrometry (LC-MS/MS) to analyze the pulled-down protein.
ORGANISM(S): Homo Sapiens 
2026-04-20 | PXD077375 |
ProteomicsComparison of the ability of exosomes and ectosomes derived from mesenchymal stem cells to promote cartilage regeneration in a rat osteochondral defect model
Background: Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) offer promising prospects for stimulating cartilage regeneration. The different formation mechanisms suggest that exosomes and ectosomes possess different biological functions. However, little attention has been paid...
ORGANISM(S): Rattus Rattus 
2023-04-01 | PXD041283 |
ProteomicsTurboID-based proximity labeling identifies reticulon-like protein B2 as a pro-viral factor coopted for the biogenesis of viral replication organelles in plants
Although intensive studies have been performed to identify and characterize host factors involved in viral replication complex formation, the high dynamism of this process and the insoluble properties of the complex make it difficult to be analyzed comprehensively using traditional affinity purifica...
ORGANISM(S): Nicotiana Benthamiana 
2023-02-12 | PXD040073 |
ProteomicsDecoding the Femoral and Tibial Entheses of the Human Anterior Cruciate Ligament
To analyze the location-specific graduated mineral composition and assembly, and mechanical transitions of the FE and TE in human knee joints.
ORGANISM(S): Homo Sapiens 
2024-10-08 | PXD056631 |
ProteomicsNanoliposuction recycles senescent cell lipids for lubrication
This study aims to systematically profile membrane protein alterations associated with chondrocyte senescence, in order to identify surface markers specifically upregulated in aged cartilage. We established two in vitro models by treating primary chondrocytes with IL-1β or bleomycin, and one in vivo...
ORGANISM(S): Mus Musculus 
2025-06-10 | PXD064867 |
ProteomicsIntegrative Proteogenomic Characterization Reveals Therapeutic Targets in Poorly Differentiated and Anaplastic Thyroid Cancers
In our study, we constructed a multicenter thyroid-cancer cohort consisting of 467 formalin-fixed paraffin-embedded (FFPE) samples, among which WES, proteome, and phosphorylated proteome analysis were conducted. Thyroid tumors consisted of 124 ATC samples, 47 PDTC samples and 177 PTC samples (includ...
ORGANISM(S): Homo Sapiens 
2025-03-16 | PXD054521 |
Sort   by:  
 Page size