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UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
MetabolomicsMechanisms of hepatic steatosis in chickens: integrated analysis of the host genome, molecular phenomes and gut microbiome

Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 70...

2023-07-24 | MTBLS7808 | MetaboLights
TranscriptomicsTranscription profiling of kidney from rats of SHR/Ola, BN and SHR-18 strains after being provided with drinking water with 1% or 0% sodium chloride
Four male SHR/Ola, BN and SHR-18 rats were fed a normal diet and sacrificed at 9 weeks of age. Four male SHR/Ola and SHR-18 rats at 8 weeks of age were fed 1% NaCl for one week and then sacrificed. Kidneys were removed and frozen in liquid nitrogen for all 20 animals. Total RNA was isolated, labelle...
ORGANISM(S): Rattus norvegicus 
2008-04-01 | E-MIMR-1122 | biostudies-arrayexpress
ProteomicsA simplified and efficient extracellular vesicles-based proteomics strategy for early diagnosis of colorectal cancer
In this work, we have developed a simplified, fast and efficient EVs-based proteomics strategy to enable biomarker discovery for early diagnosis of CRC. By covalent conjugation of an EV-targeting probe, DSPE, to agarose beads, we achieved one-step enrichment of EVs from plasma fluids in 10 minutes w...
ORGANISM(S): Homo Sapiens 
PXD054231 |
ProteomicsAnalysis of differentially expressed proteins （DEPs） in tomato leaves under the abaxial leafy supplemental lightning (AB) and the adaxial leafy supplemental lightning (AD)
Analysis of differentially expressed proteins （DEPs） in tomato leaves under the abaxial leafy supplemental lightning (AB) and the adaxial leafy supplemental lightning (AD)
ORGANISM(S): Solanum Lycopersicum 
2022-11-18 | PXD038211 |
ProteomicsiTRAQ proteomics reveals the regulatory response to Magnaporthe oryzae in durable resistant vs. susceptible rice genotypes
Here, we used the iTRAQ method to detect the differentially expressed proteins (DEPs) in the durable resistant rice variety Gangyuan8 (GY8) and the susceptible rice variety Lijiangxintuanheigu (LTH) in response to M. oryzae invasion, and then transcriptome sequencing was used to assist analysisA tot...
ORGANISM(S): Oryza Sativa 
2019-12-09 | PXD016645 |
ProteomicsVCP enhances autophagy-related osteosarcoma progression by recruiting USP2 to inhibit ubiquitination and degradation of FASN
The mass spectrometry data were acquired using a Q Exactive HF mass spectrometer coupled with an UltiMate 3000 RSLCnano liquid chromatography system. Peptide samples were dissolved in a loading buffer, introduced via an autosampler, and separated on an analytical column (75 μm × 25 cm, C18, 1.9 μm, ...
ORGANISM(S): Homo Sapiens 
PXD055763 |
ProteomicsUSP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway
Knock down the expression level of USP3 in osteosarcoma cell 143B and observe the proteins with altered ubiquitination levels.
ORGANISM(S): Homo Sapiens 
2024-02-20 | PXD049717 |
ProteomicsZJ5 and 025 interact protein LC-MS
IP and LS-MS to identify the interact protein of ZJ5 and 025 in Saccharomyces cerevisiae
ORGANISM(S): Saccharomyces Cerevisiae 
PXD053002 |
ProteomicsThe proteomic navigator of human aging
Proteins are the cornerstone of human life, yet the proteomic landscape of aging across human tissues remains largely unexplored. Here, we present a comprehensive proteomic analysis of 520 samples from 15 human tissues, spanning a 50-year lifespan. Our study compiles a proteomic encyclopedia of mult...
ORGANISM(S): Homo Sapiens 
2024-12-06 | PXD058638 |
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