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UnknownKun-Dan Decoction Ameliorates Insulin Resistance by Activating AMPK/mTOR-Mediated Autophagy in High-Fat Diet-Fed Rats.
Not available
S-EPMC8193673 | biostudies-literature
MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
MetabolomicsPatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
Glycolipids and lipids are prominent components of bacterial cell wall that play critical roles not only in maintaining the biofilm formation but also in resistance to environmental stress. PatA is an essential membrane associated acyltransferase involved in the biosynthesis of phosphatidyl-myo-inos...
2023-05-22 | MTBLS6758 | MetaboLights
TranscriptomicsA genetics screen highlights emerging roles for CPL3, RST1 and URT1 in RNA metabolism and silencing (small RNA profiling part)
CPL3, RST1 and URT1 are three new genes involved in RNA metabolism and suppressing RNA silencing in Arabidopsis. To investigate how transcripts and small RNAs varies in the absence of them, RNA and small RNA sequencing were performed on the shoot tissues of 17-day-old EMS mutants of CPL3, URT1 or RS...
ORGANISM(S): Arabidopsis thaliana 
2019-05-03 | E-MTAB-7874 | biostudies-arrayexpress
UnknownAlpine Grassland Ecological Restoration Approaches Shape Insect Trophic Guild Diversity: A Multi-Dimensional Assessment from Alpha to Dark Diversity.
Not available
S-EPMC12653117 | biostudies-literature
ProteomicsHuman hela cells mitochondrial LC-MS
We extracted mitochondria from Hela cells which were treated with CCCP or DMSO for 2 h. The samples were digested by FAST and peptides were used DIA to analysis.
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD016400 | Pride
Mitophagy 
MetabolomicsUPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females

Although previous studies have shown that certain factors interfere with the sensitivity of propofol, the mechanisms for interindividual variability in response to propofol remain unclear. This study aimed to screen the metabolites to predict patients' sensitivity to propofol and to identify meta...

2021-09-29 | MTBLS2311 | MetaboLights
UnknownThe anti-PD-L1/CTLA-4 bispecific antibody KN046 plus lenvatinib in advanced unresectable or metastatic hepatocellular carcinoma: a phase II trial.
Not available
S-EPMC11806070 | biostudies-literature
MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
TranscriptomicsLudwig Institute/UCSD ENCODE project August 2007 Release
The readout of genome information is controlled by transcriptional regulatory elements, but a comprehensive view of the combinatorial control by these DNA sequences, which bind regulatory protein and/or the modified histones in regulating gene transcription, is clearly preliminary. We have developed...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-8887 | biostudies-arrayexpress
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