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MetabolomicsComprehensive Untargeted Metabolomics Dataset of Saccharomyces cerevisiae Aging-Associated Mutants and Yeast–Host Interactions in Drosophila melanogaster

Aging is a complex biological process influenced by genetic factors, environmental conditions, and interactions between organisms and their associated microbes. The budding yeast Saccharomyces cerevisiae and the fruit fly Drosophila melanogaster provide complementary model systems for investigati...

2026-09-04 | MTBLS15555 | MetaboLights
UnknownAhf-Caltide, a Novel Polypeptide Derived from Calpastatin, Protects against Oxidative Stress Injury by Stabilizing the Expression of CaV1.2 Calcium Channel.
Not available
S-EPMC10648788 | biostudies-literature
TranscriptomicsWhole genome expression signature of SWCNT and MWCNT vs. asbestos subchronic exposures to human pleural mesothelial cells
Malignant mesothelioma is one of the most aggressive forms of cancer known. Recent studies have shown that carbon nanotubes (CNTs) are biopersistent and induce mesothelioma in animals, but the underlying mechanisms are not known. Here, we investigate the effect of long-term exposure to CNTs on the a...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-48855 | biostudies-arrayexpress
UnknownEvolution of a bispecific G-quadruplex-forming circular aptamer to block IL-6/sIL-6R interaction for inflammation inhibition.
Not available
S-EPMC11323322 | biostudies-literature
TranscriptomicsWhole genome profile of SWNCT and MWCNT vs. asbestos subchronic exposures to human small airway epithelial cells
Recent in vivo studies reported that inhaled carbon nanotube distribute in the alveolar region resulting in an acute inflammation, progressive fibrotic response and particle accumulation at the bronchoalveolar junction with low clearance. With similar biopersistence and shape as asbestos, a known l...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-41178 | biostudies-arrayexpress
UnknownThe crucial role of neutrophil extracellular traps and IL-17 signaling in indomethacin-induced gastric injury in mice.
Not available
S-EPMC11982219 | biostudies-literature
MetabolomicsMulti-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
Endometrial cancer (EC) is one of the most common gynecological cancers. Finding biomarkers of EC can support its diagnosis in a non- or minimally-invasive way. In this work, we integrated metabolomics and proteomics for the analysis of multiple types of biosamples to gain a more comprehensive view ...
2022-03-28 | MTBLS3935 | MetaboLights
TranscriptomicsDifferentially expressed long noncoding RNA expression between periodontal ligament stem cells from healthy periodontal tissue and periodontal ligament stem cells from inflammatory periodontal tissue.
Periodontitis can impair the osteogenic differentiation of human periodontal mesenchymal stem cells, but the underlying molecular mechanisms are still poorly understood. Long noncoding RNAs (lncRNAs) have been demonstrated to play significant roles under both physiologic and pathological conditions....
ORGANISM(S): Homo sapiens 
2016-02-19 | E-GEOD-78074 | biostudies-arrayexpress
GenomicsEpigenomic landscape during organ formation in human early embryos
Here we present the whole genome ChIP-Seq analyses of a wide variety of histone marks, H3K27ac, H3K4me1, H3K4me3, and H3K27me3 in the brain, heart, and liver, along with the RNA-seq data of these organs of early human embryos 12 weeks after gestation. In total, brain, heart, and liver of early human...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-63634 | biostudies-arrayexpress
UnknownRevisiting the structure of the Yale Global Tic Severity Scale (YGTSS) in a sample of Chinese children with tic disorders.
Not available
S-EPMC8351146 | biostudies-literature
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