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UnknownA review on Gaucher disease: therapeutic potential of β-glucocerebrosidase-targeted mRNA/saRNA approach.
Not available
S-EPMC11008270 | biostudies-literature
UnknownPlant immune inducer ZNC promotes rutin accumulation and enhances resistance to Botrytis cinerea in tomato.
Not available
S-EPMC10444710 | biostudies-literature
MetabolomicsThe gut microbiota-butyrate axis restores cardiomyocyte autophagy to alleviate Doxorubicin-induced cardiotoxicity

Abstract

Background Doxorubicin (DOX), an anthracycline chemotherapeutic agent, is widely used for treating various malignancies. However, its clinical application is limited by dose-dependent cardiotoxicity (DOX-induced cardiotoxicity, DIC). Recent studies have shown that the gut microbiot...

2025-09-16 | MTBLS12997 | MetaboLights
ProteomicsG3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer
SPOP, an E3 ubiquitin ligase, acts as a prostate-specific tumor suppressor with several key substrates mediating oncogenic function. However, the mechanisms underlying SPOP regulation are largely unknown. Here, we have identified G3BP1 as an interactor of SPOP and functions as a competitive inhibito...
ORGANISM(S): Homo sapiens (Human) 
2021-11-25 | PXD029120 | Pride
Tap-ms Human Spop G3bp1 Prostate cancer 
ProteomicsProteomic signatures in chronic obstructive pulmonary disease emphysematous phenotype
Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous disease. Emphysematous phenotype is a type of most common and critical phenotype, which is characterized by progressive lung destruction and poor prognosis. However, the underlying mechanism of this structural damage has not been...
ORGANISM(S): Homo Sapiens 
2021-01-31 | PXD023900 |
ProteomicsdiaPASEF analysis of exosomes from stem cells
we used highly sensitive mass spectrometry diaPASEF (parallel accumulation serial fragmentation combined with the data-independent acquisition)27 to quantify proteins of exosomes derived from umbilical cord mesenchymal stem cells (UCMSCs) and rat bone marrow stem cells (BMSCs). 4206 human proteins a...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2022-05-05 | PXD033723 |
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