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DHX15 has been implicated in RNA splicing and ribosome biogenesis, primarily functioning as an RNA helicase. To systematically assess the cellular role of DHX15, we conducted proteomic analysis to investigate the landscape of DHX15 interactome, and identified MYC as a binding partner. DHX15 co-local...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046692 | Pride

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
The trabecular meshwork (TM) responsible for IOP homeostasis in the eye could sense the IOP fluctuations dynamically and adapt to the mechanical changes appropriately. Cationic mechanosensitive channels (CMCs) have been reported with critical roles in mediating the TM responding to many mechanical f...
ORGANISM(S): Homo Sapiens 
2022-03-14 | PXD032288 |
Primordial germ cells (PGCs) are precursors of both male and female gametes as fundamental materials for organism development. The transcriptome, methylome and chromatin accessibility profiles of PGCs in both mice and humans have been recently reported. However, little is known about the characteris...
ORGANISM(S): Mus Musculus 
Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity, PPI of ZMYND11 in LNCap
ORGANISM(S): Homo Sapiens 
Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity, To investigate the function of ZMYND11 in prostate cancer, We performed Co-IP and mass-spectometry (MS) analysis of ZMYND11.
ORGANISM(S): Homo Sapiens 
study the differentially expressed proteins in esophageal squamous cell carcinoma
ORGANISM(S): Homo Sapiens 
Early screening is essential for the treatment of colorectal cancer (CRC). Concerns are rising regarding liquid biopsy due to its low invasiveness and reproducibility, especially when tissue samples are not available. Recent reports suggest that tumor-specific proteins may be stably expressed in exo...
ORGANISM(S): Homo Sapiens 
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