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TranscriptomicsTranscriptome-wide Regulation of Splicing and mRNA Localization by Muscleblind Proteins
The Muscleblind-like (Mbnl) family of RNA-binding proteins plays important roles in muscle and eye development and in Myotonic Dystrophy (DM), where expanded CUG or CCUG repeats functionally deplete Mbnl proteins. We identified transcriptome-wide functional and biophysical targets of Mbnl proteins i...
ORGANISM(S): Drosophila melanogaster 
2012-08-17 | E-GEOD-39911 | biostudies-arrayexpress
UnknownIdentification of potential serum biomarkers of acute paraquat poisoning in humans using an iTRAQ quantitative proteomic.
Not available
S-EPMC9078879 | biostudies-literature
ProteomicsIntegrative proteomic characterization of human lung adenocarcinoma
Genomic studies of lung adenocarcinoma (LUAD) have advanced understanding of the disease’s biology and accelerated targeted therapy. However, proteomic characteristics of LUAD remain poorly understood. We carried out comprehensive proteomic analysis of 103 cases of LUAD in Chinese patients. Integrat...
ORGANISM(S): Homo Sapiens 
2020-07-10 | PXD020252 |
UnknownGiant tuning of ferroelectricity in single crystals by thickness engineering.
Not available
S-EPMC7556833 | biostudies-literature
ProteomicsUtilizing Liquid Biopsy-Derived Extracellular Vesicle Protein Biomarkers for Diagnosis and Prognostic Assessment in Lung Squamous Cell Carcinoma
In the context of pulmonary nodules detected in imaging, there is currently a lack of highly effective and non-invasive methods for both diagnosing and prognosticating lung squamous cell carcinoma (LUSC). Therefore, in this study, we explored the potential of plasma-derived extracellular vesicles (E...
ORGANISM(S): Homo Sapiens 
2023-12-18 | PXD047893 |
Proteomics4D label free phosphorylation modification omics of 60 human esophageal cancer tissue samples
Phosphoproteome analysis of clinical tissue samples is important in the precision medicine research. Therefore, we used LC-MS/MS to systematically analyze the differential phosphorylation levels of 20 ESCC tumor tissues, paired normal tissue and lymph node metastatic tissue.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD051858 | Pride
Esophageal cancer Phosphorylation Human Lc-ms/ms 
ProteomicsPhysical exercise in combination with audiovisual stimulation alleviates cognitive and affective impairments in Alzheimer's disease model mice
This project focus on the proteomic changes in AD model mice. AD model mice were established by injecting Aβ₄₂ oligomers into the hippocampus. These mice were then subjected to treadmill training(ADE), 40 Hz audio-visual stimulation(ADVL), or a combination of these interventions(ADEVL). Quantitative...
ORGANISM(S): Mus Musculus 
2026-04-27 | PXD077685 |
TranscriptomicsRNA-seq of rat dorsal root ganglia after ligation to investigate central nervous system transcriptomics in chronic pain using agnostic splice site discovery methods
The study pursued dual goals: To advance mRNA-seq bioinformatics towards unbiased transcriptome capture and to demonstrate its potential for discovery in neuroscience by applying the approach to an in vivo model of neurological disease. We found that 12.4% of known genes were induced and 7% were sup...
ORGANISM(S): Rattus norvegicus 
2010-05-01 | E-GEOD-20895 | biostudies-arrayexpress
TranscriptomicsFull-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
We assessed Smart-Seq, a new single-cell RNA-Seq library preparation method, on a variety of mouse and human RNA samples or cells. We generated RNA-Seq libraries for dilution series of MAQC reference RNA and mouse brain RNA to assess technical reproducibility, and for a variety of individual cells i...
ORGANISM(S): Homo sapiens 
2012-07-22 | E-GEOD-38495 | biostudies-arrayexpress
UnknownHigh piezoelectric property with exceptional stability in self-poled ferroelectric films.
Not available
S-EPMC11685493 | biostudies-literature
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