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ProteomicsDeep proteomic and phosphoproteomic profiling of DIPG responses to radiation therapy
Different DIPG tumor models have different responses to radiation therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD028285 | Pride
Cancer Radiation therapy Phosphoproteome Dipg Proteome 
ProteomicsDeep proteomic and phosphoproteomic profiling of Rhabdoid tumor response to IDA/SEL therapy
Different Rhabdoid tumors have different responses to idasanultin/selinexor therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD049344 | Pride
Human Pediatric Selinexor Idasanutlin Rhabdoid 
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
TranscriptomicsRNA-seq of mouse embryonic stem cells with knockout of Nhlrc2 gene or addition of FINCA disease causing NHLRC2 p.Asp148Tyr variant
Fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA) (OMIM 618278) is a rare infantile-onset disease caused by variants in NHL repeat containing 2 (NHLRC2) gene. NHLRC2 is essential for mouse gastrulation (Hiltunen et al., 2022). Here, RNA sequencing was performed on four wild type (WT), f...
ORGANISM(S): Mus musculus 
2025-05-22 | E-MTAB-14174 | biostudies-arrayexpress
ProteomicsProteome profiling of mouse germinal center B cells
Productive B cell responses are critical to protect a host from infection. The spleen and lymph nodes are populated by resting follicular B cells, which can enter germinal centers upon antigen encounter. Once in the germinal center, B cells migrate between the dark and light zones, where they underg...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-06 | PXD015524 | Pride
Mouse B cells 
ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
TranscriptomicsIdentifying molecular mechanisms of neural crest (NC) EMT and cell migration
Purpose: To identify differntially expressed transcripts in TP-0903 treated embryos that impair cranila NC EMT and cell migration in zebrafish embryos Methods: zebrafish embryos treated at 13 hpf with 5-7uM TP-0903 and DMSO for 1-, 4- and 8-hrs at 28°C. 35 embryos were collected for each treatment....
ORGANISM(S): Danio rerio 
2016-02-18 | E-GEOD-72322 | biostudies-arrayexpress
UnknownEfficacy and safety of elagolix with add-back therapy in women with uterine fibroids and coexisting adenomyosis.
Not available
S-EPMC8441572 | biostudies-literature
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
TranscriptomicsAn initial map of chromosomal segmental copy number variations in chickens
Chromosomal segmental copy number variation (CNV) has been recently recognized as a very important source of genetic variability. Some CNV loci involve genes or conserved regulatory regions. Compelling evidence indicates that CNVs impact genome functions. The chicken is a very important farm animal ...
ORGANISM(S): Gallus gallus 
2010-06-11 | E-GEOD-19469 | biostudies-arrayexpress
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