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TranscriptomicsDiscovery of novel recurrent mutations and rearrangements in early T-cell precursor acute lymphoblastic leukemia by whole genome sequencing
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole genome sequencing of tumour and normal DNA from 12 children with ETP ALL and assessed the frequency of somatic alterations in 52 ETP and 42 non-ETP T-ALL samples by...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-28703 | biostudies-arrayexpress
UnknownIncreased CaV1.2 late current by a CACNA1C p.R412M variant causes an atypical Timothy syndrome without syndactyly.
Not available
S-EPMC9643354 | biostudies-literature
UnknownMicroRNA profile in neosquamous esophageal mucosa following ablation of Barrett's esophagus.
Not available
S-EPMC5558114 | biostudies-literature
TranscriptomicsTranscription profiling of mouse splenic and small intestine lamina propria macrophages
The intestinal immune system must elicit robust immunity against harmful pathogens but restrain immune responses directed against commensal microbes and dietary antigens. The mechanisms that maintain this dichotomy are poorly understood. Here we describe a population of CD11b+F4/80+CD11câ?? macroph...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8868 | biostudies-arrayexpress
TranscriptomicsExploring the mechanism of C4 photosynthetic differentiation through a unified comparative analysis of maize and rice leaf transcriptomes
Maize and rice are the two most economically important grass crops and utilize distinct forms of photosynthesis to fix carbon: C4 and C3 respectively. Relative to C3 photosynthesis, C4 photosynthesis reduces photorespiration and affords higher water and nitrogen use efficiencies under hot arid condi...
ORGANISM(S): Zea mays 
2014-10-12 | E-GEOD-54274 | biostudies-arrayexpress
UnknownRandomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results.
Not available
S-EPMC4820756 | biostudies-literature
TranscriptomicsTranscription profiling of mouse model of Helicobacter-induced gastric cancer
We have previously reported human gastrin overexpressing transgenic mice (=INS-GAS mice) and Helicobacter felis (=H.felis) infection synergistically accelerated gastric cancer in mice stomachs. (Wang et al 2000) Using this mouse model, we employed microarray analysis of gene expression profiling t...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4651 | biostudies-arrayexpress
GenomicsMus musculus
Effect of Tff2 on mouse Gr1+Cd11b+
PRJNA206463 | ENA
UnknownRandomized phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small-cell lung cancer: Cancer and Leukemia Group B trial 30407.
Not available
S-EPMC3157978 | biostudies-literature
GenomicsMorphine treatment induces distinct changes in the gut microbiome at day 3 post treatment
Opioids such as morphine have many beneficial properties as analgesics, however, opioids may induce multiple adverse gastrointestinal symptoms. We have recently demonstrated that morphine treatment results in significant disruption in gut barrier function leading to increased translocation of gut co...
ORGANISM(S): mouse gut metagenome 
2018-04-16 | E-MTAB-5546 | biostudies-arrayexpress
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