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MetabolomicsSystem Xc- exacerbates metabolic stress under glucose depletion in oral squamous cell carcinoma

OBJECTIVE: Emerging evidence suggests that glucose depletion (GD)-induced cell death depends on system Xc-, a glutamate/cystine antiporter extensively studied in ferroptosis. However, the underlying mechanism remains debated. Our study confirmed the correlation between system Xc...

2024-01-16 | MTBLS5358 | MetaboLights
UnknownATF3 promotes erastin-induced ferroptosis by suppressing system Xc.
Not available
S-EPMC7206049 | biostudies-literature
MetabolomicsComparison of Chemical Compositions in Pseudostellariae Radix from Different Cultivated Fields and Germplasms by NMR-Based Metabolomics
Pseudostellariae Radix (PR) is an important traditional Chinese medicine (TCM), which is consumed commonly for its positive health effects. However, the chemical differences of PR from different cultivated fields and germplasms are still unknown. In order to comprehensively compare the chemical comp...
2018-01-25 | MTBLS399 | MetaboLights
UnknownTricistronic hepatitis C virus subgenomic replicon expressing double transgenes.
Not available
S-EPMC4277965 | biostudies-literature
Unknown8-weeks aerobic exercise ameliorates cognitive deficit and mitigates ferroptosis triggered by iron overload in the prefrontal cortex of APP Swe/PSEN 1dE9 mice through Xc-/GPx4 pathway.
Not available
S-EPMC11417105 | biostudies-literature
UnknownUrsolic acid induces colorectal cancer cells ferroptosis via regulation of system xc<sup>-</sup> and miR-214-3p/Stat3/GPX4 axis.
Not available
S-EPMC12668971 | biostudies-literature
UnknownDirect conversion of various phosphate sources to a versatile P-X reagent [TBA][PO2X2] via redox-neutral halogenation.
Not available
S-EPMC11865473 | biostudies-literature
UnknownBreast cancer cells have an increased ferroptosis risk induced by system xc- blockade after deliberately downregulating CYTL1 to mediate malignancy.
Not available
S-EPMC10821163 | biostudies-literature
UnknownViolashiweii, a new species of Viola (Violaceae) from karst forest in Guizhou, China.
Not available
S-EPMC9848997 | biostudies-literature
ProteomicsAcetylation Coordinates the Crosstalk between Carbon Metabolism and Ammonium Assimilation
Enteric bacteria use up to 15% of their cellular energy for ammonium assimilation via glutamine synthetase (GS)/glutamate synthase (GOGAT) and glutamate dehydrogenase (GDH), in response to low or high ammonium availability. However, the sensory mechanisms for effective and appropriate coordination b...
ORGANISM(S): Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
2023-06-21 | PXD039658 | Pride
Ammonium assimilation Acetylation Coordination Carbon metabolism 
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