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TranscriptomicsTranscription profiling of thymocytes from Kruppel-like transcription factor (KLF)13 knock-out mice
Kruppel-like transcription factor (KLF)13, previously shown to regulate RANTES expression in vitro, is a member of the Kruppel- like family of transcription factors that controls many growth and developmental processes. To ascertain the function of KLF13 in vivo, Klf13-deficient mice were generated ...
ORGANISM(S): Mus musculus 
2007-05-11 | E-SMDB-4035 | biostudies-arrayexpress
ProteomicsEnabling Photoactivated Cross-linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-cleavable Cross-linkers
Cross-linking mass spectrometry (XL-MS) is a powerful tool for studying protein-protein interactions and elucidating architectures of protein complexes. While residue-specific XL-MS studies have been very successful, accessibility of interaction regions non-targetable by specific chemistries remain ...
ORGANISM(S): Bos taurus (Bovine) Saccharomyces cerevisiae (Baker's yeast) 
2021-05-07 | PXD022690 | Pride
26s proteasome Photocross-linking Sdaso Bsa 
ProteomicsProteomic dynamic changes in HDL subfractions from mouse plasma
HDL proteome dynamics may determine HDL cardioprotective functions. We aimed to characterize proteome and lipid profiles in small, medium and large (S/M/L) HDL fractions and analyze their functions. We characterized mouse HDL fractions by their high phospholipid (PL) content and collected S/M/L-HDL...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD011185 | Pride
Plasam Mouse Esi-ms/ms Hdl subfractions Hdl 
UnknownBcl-xL DNAzymes promote radiosensitivity and chemosensitivity in colorectal cancer cells via enhancing apoptosis.
Not available
S-EPMC8817578 | biostudies-literature
UnknownStructure-Based Design of A-1293102, a Potent and Selective BCL-XL Inhibitor.
Not available
S-EPMC8201748 | biostudies-literature
UnknownMDM2-BCL-XL PROTACs enable degradation of BCL-XL and stabilization of p53.
Not available
S-EPMC10004178 | biostudies-literature
UnknownAnti-apoptotic protein BCL-XL as a therapeutic vulnerability in gastric cancer.
Not available
S-EPMC10272913 | biostudies-literature
UnknownStructure-Guided Rescaffolding of Selective Antagonists of BCL-XL.
Not available
S-EPMC4060937 | biostudies-literature
UnknownBCL-xL is a target gene regulated by hypoxia-inducible factor-1{alpha}.
Not available
S-EPMC2665055 | biostudies-literature
UnknownTargeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma.
Not available
S-EPMC10393801 | biostudies-literature
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