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MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
TranscriptomicsClaudin 1 mediates TNF alpha-induced gene expression and cell migration in human lung carcinoma cells
Epithelial-mesenchymal transition (EMT) is an important mechanism in carcinogenesis. To determine the mechanisms that are involved in the regulation of EMT is crucial to develop new biomarkers and therapeutic targets towards cancers. In this study, when TGFß1 and TNFa were used to induce EMT in hum...
ORGANISM(S): Homo sapiens 
2012-06-12 | E-GEOD-32254 | biostudies-arrayexpress
ProteomicsKLF16 enhances stress tolerance of colorectal carcinomas by modulating nucleolar homeostasis and translational reprogramming
Translational reprogramming is part of the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress, which acts to the advantage of cancer growth and development in different stress conditions. But the mechanism of ER stress-related translational reprogramming in colorectal carcinoma...
ORGANISM(S): Homo Sapiens 
2022-05-16 | PXD033930 |
ProteomicsGreen production of alginate oligosaccharides from Laminaria japonica root by fermentation of a Laminaria japonica-degrading strain Pseudoaltermonas sp. A3
To identify carbohydrate-active enzymes in the secretome of strain A3 when L. japonica was the sole carbon source and key alginate lyases in the supernatant of fermentation broth.
ORGANISM(S): Pseudoalteromonas Sp. A3 
2022-11-30 | PXD037880 |
ProteomicsIdentification of exogenously expressed RBRP-GFP peptide
The exogenously expressed RBRP-GFP peptide encoded by lncRNA LINC00266-1 was validated by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2020-02-25 | PXD016267 |
ProteomicsIdentification of endogenous, natural RBRP peptide encoded by lncRNA LINC00266-1 in tumor tissue
The total proteins from tumor tissues were seperated by tricine SDS-PAGE and stained with silver. The gel band with about 7kD molecular weight related to RBRP peptide was identified by LC-MS/MS.
ORGANISM(S): Homo Sapiens 
2020-02-25 | PXD016268 |
ProteomicsIdentification the interactors of the K235-acetylated ALKBH5
The differntial gel band between wild-type ALKBH5-interacted proteins and K235R mutant ALKBH5-interacted proteins was identifed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD020071 |
ProteomicsIdentification of the acetylation sites in ALKBH5
The acetylation modification sites in ALKBH5 was identified by mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD020070 |
ProteomicsCharacterization of proteome variation during modern maize breeding
we used mass spectrometto perform an integrated analysis of proteome e in an association panel consisting of 98 maize inbred lines.
ORGANISM(S): Zea Mays 
2019-01-17 | PXD042776 |
ProteomicsThe novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L
Here, by state-of-the-art mass spectrometry-based quantitative proteomic technology, we systematically screened the potential neo-substrates of a novel thalidomide derived cereblon modulator CC-885.
ORGANISM(S): Homo Sapiens 
2020-01-11 | PXD017071 |
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