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TranscriptomicsFY-hESC Micro-array raw data
Human embryonic stem cells (hESCs) exhibit a skewed X chromosome inactivation (XCI) have recently been reported. Whether there is any copy number variation (CNV), loss of heterozygousity (LOH) and single nucleotide variant (SNV) in those epigenetically distinct cells and whether these abnormalities ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-MTAB-1992 | biostudies-arrayexpress
TranscriptomicsGene mRNA levels in the bone of FAM20C KO mice VS WT mice (3-WK-old)
Family with sequence similarity 20-member C (FAM20C) is a new molecule that is highly expressed in the mineralized tissues of mammals. Genetic studies showed that the loss-of-function mutations in FAM20C were associated with human lethal osteosclerotic bone dysplasia (Raine Syndrome), indicating tha...
ORGANISM(S): Mus musculus 
2012-02-17 | E-MTAB-772 | biostudies-arrayexpress
UnknownChinese acupuncture: A potential treatment for autism rat model via improving synaptic function.
Not available
S-EPMC11402746 | biostudies-literature
ProteomicsIn-depth site-specific O-glycosylation analysis of glycoproteins and endogenous peptides in cerebrospinal fluid (CSF) from healthy individual mild cognitive impairment (MCI) and Alzheimer disease (AD) patients
Site-specific O-glycoproteome mapping in complex biological system provides molecular basis for understanding the structure-function relationships of glycoproteins and their roles in physiological and pathological processes. Previous O-glycoproteome analysis in cerebrospinal fluid (CSF) focused on s...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-05 | MSV000087160 | MassIVE
TranscriptomicsExpression data from peripheral blood mononuclear cell in patients with type 1 diabetes before and after peripheral stem cell transplantation
Autologous nonmyeloablative hematopoietic stem cell transplantation (AHST) was the first therapeutic approaches that can improve beta cell function in type 1 diabetic (T1D) patients. This study was designed to investigate the potential mechanisms involved.We applied AHST to nine T1D patients diagnos...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-29908 | biostudies-arrayexpress
ProteomicsPorcine spermatozoa proteomics and phosphoproteomics analysis
In this research, we have used a global analysis of iTRAQ-based quantitative proteome coupled with phosphopeptide-enrichment strategies to reveal the boar spermatozoa proteome and find the PTMs associated with the breeds differences using Yorkshire and Duroc boar spermatozoa.
ORGANISM(S): Sus Scrofa 
2021-04-23 | PXD025607 |
Proteomicsaortic dissection molecular markers using iTRAQ combined with Label Free techniques
To screen serum molecular markers systematically amid aortic dissection and acute coronary syndrome, preliminary identify the pathogenesis of acute aortic dissection.
ORGANISM(S): Homo Sapiens 
2022-03-25 | PXD032857 |
ProteomicsDifferential proteomic and phosphoproteomic analysis of Hnrnpk conditional knockout mouse testes
In this research, we have used a global analysis of TMT-based quantitative proteome coupled with phosphopeptide-enrichment strategies to reveal the mouse testes proteome and find the PTMs associated with the RNA binding protein hnRNPK using Hnrnpk conditional knockout mouse and WT mouse testes.
ORGANISM(S): Mus Musculus 
2024-09-14 | PXD056125 |
ProteomicsBispecific antigen therapy plasma proteome
Bispecific-antibody therapy (BAT), the next strategy of immunotherapy for tumor patients, has showed the enhanced antitumor benefits than the monotherapy. Yet, few effective biomarkers were developed to monitor the response. Here, we investigated the first BAT longitudinal plasma proteome profiling ...
ORGANISM(S): Homo Sapiens 
2024-02-20 | PXD039260 |
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