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X-linked retinoschisis (XLRS) is among the most common inherited degenerative retinopathies. Functional impairment of RS1 protein is the cause of XLRS, which presents childhood onset with typical structural and functional alterations. However, the molecular mechanisms underlying RS1 malfunction rema...
ORGANISM(S): Mus Musculus 
2022-02-27 | PXD031901 |
the proteome of skin lesions from HHD patients was assembled and used for iTRAQ to analyze changes in skin lesions compared with unaffected individuals.
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD006286 | Pride
The mechanisms underlying cancer metastasis remain poorly understood. Here, we report that TFAM deficiency rapidly and stably induced spontaneous lung metastasis in mice with liver cancer. Interestingly, unexpected polymerization of nuclear actin was observed in TFAM-knockdown HCC cells when cytoske...
2022-06-23 | MTBLS4307 | MetaboLights

BACKGROUND: It has been reported that the gut microbiome is involved in the pathogenesis of uveitis, but the specific pathogenic microbes and metabolites in different types of uveitis are still unclear.

METHODS:&...

2023-12-12 | MTBLS7936 | MetaboLights
1 million MDAMB231 cells were seeded in 6-well plates. On the following day, MBAMB231 cells were treated in triplicates with DMSO, LD4172 (100 nM) or LD4172-NC (100 nM) for 6 hours. Cells were washed with ice-cold PBS three times. The cell pellets were lysed, reduced, alkylated, and digested by Easy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-07 | MSV000092377 | MassIVE
1 million MDAMB231 cells were seeded in 6-well plates. On the following day, MBAMB231 cells were treated in triplicates with DMSO, LD4172 (100 nM) or LD4172-NC (100 nM) for 6 hours. Cells were washed with ice-cold PBS three times. The cell pellets were lysed, reduced, alkylated, and digested by Easy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-05 | MSV000092348 | MassIVE

Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 70...

2023-07-24 | MTBLS7808 | MetaboLights
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