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To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to systematic proteomic.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD037295 | Pride
We analyzed the lactylomes and proteomes of infarcted myocardium in mice subjected to sham treatment, myocardial infarction (MI) for 30 min or MI followed by I/R for 6 h using liquid chromatography-tandem mass spectrometry (LC–MS/MS) system.
ORGANISM(S): Mus musculus (Mouse) 
2024-11-20 | PXD046631 | Pride
O2- and O4-alkylated thymidine lesions are known to be poorly repaired and persist in mammalian tissues. To understand how mammalian cells sense the presence and regulate the repair of these lesions, we employed a stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative prot...
ORGANISM(S): Homo sapiens (Human) 
2020-12-21 | PXD021719 | Pride
L-Oligonucleotides (ONs), the synthetic enantiomer of native D-nucleic acids, are being increasingly utilized for the development of diverse biomedical technologies, including molecular imaging tools, diagnostic biosensors, and aptamer-based therapeutics. Nevertheless, our understanding of how L-ONs...
ORGANISM(S): Homo sapiens (Human) 
2025-03-13 | PXD054780 | Pride
Serum samples were collected from patients with PsA to create a biomarker discovery cohort and a validation cohort. Patients with PsA were classified into axial or peripheral subtypes based on imaging criteria. Liquid chromatography-mass spectrometry was used in the discovery phase to screen for bio...
ORGANISM(S): Homo Sapiens 
Hepatocellular carcinoma is one of the most frequently diagnosed cancers in the world. Post-translational modifications (PTMs) play an essential role during cancer development. Phosphorylation is an important PTMs. To identify the modifications of phosphorylation in HCC, a multiplexed tandem mass ta...
ORGANISM(S): Homo sapiens (Human) 
2021-01-14 | PXD013934 | Pride
In total, 5,840 protein groups were identified, among which 5,188 proteins were quantified. The fold-change cutoff was set when proteins with quantitative ratios above 1.5 or below 0.667 are deemed significant. Among the quantified proteins, 95 proteins are up-regulated and 155 proteins are down-reg...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-11-12 | PXD011814 | Pride
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