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We conducted an RNA pulldown assay in Hepatocellular carcinoma cell line HepG2 using in vitro-transcribed full-length LINC01186 RNA accompanied with a control EGFP RNA. The specific binding proteins of LINC01186 was identified using high-performance liquid chromatography-mass spectrometry (HPLC-MS).
ORGANISM(S): Homo sapiens (Human) 
2022-07-23 | PXD031844 | Pride
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that impacts neurons in the brain and spinal cord. Although a substantial number of studies have been conducted, much remains to be learned about the cellular mechanisms underlying ALS. In this study, we employed an engineered ascor...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD050785 | Pride
We conducted HPLC-MS analysis of the protein mix immunoprecipitated by SIRT7 antibody under non-IR and 8 Gy X-ray irradiation to identify the interacting proteins of SIRT7 in HaCaT cells.
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD033924 | Pride
Mutations in SOD1 (Superoxide Dismutase 1) gene are associated with amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. By employing ascorbate peroxidase (APEX)-based proximity labeling, coupled with LC-MS/MS analysis, we uncovered 37 and 28 proteins exhibiting higher abundance i...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-01-26 | PXD035452 | Pride
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