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TranscriptomicsCharacterization of gene expression profile in HBV-related liver fibrosis patients
Hepatitis B virus (HBV) infection is a leading risk factor for liver fibrosis (LF) and hepatocellular carcinoma. Emerging evidence indicates that host genetic, virological and immunological factors will influence the fibrotic progress. Many previous studies have focused on specific pathways or genes...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-84044 | biostudies-arrayexpress
ProteomicsAn integrated metabolomics and lipidomics approach for the study of metabolic network and early diagnosis in cerebral infarction
Cerebral infarction (CI) remains a major cause of high mortality and long-term disability worldwide. The exploration of biomarkers and pathogenesis is crucial for early diagnosis of CI. Although the understanding of metabolic perturbations underlying CI has increased in recent years, the relationshi...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036199 | Pride
Metabolomics Cerebral infarction Lc-ms Lipidomics Biomarkers 
MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
UnknownLipoprotein(a) is a new prognostic factor in patients with psoriasis and coronary artery disease: a retrospective cohort study.
Not available
S-EPMC10474627 | biostudies-literature
UnknownDiabetes is associated with a poor prognosis in patients with psoriasis and coronary artery disease.
Not available
S-EPMC12257814 | biostudies-literature
ProteomicsScreening human protein interacting with mGluR2
Through mass spectrometry to obtain a high-quality mGluR2 interactome, screened host factors interacting with mGluR2. The experiment was repeated three times.
ORGANISM(S): Homo Sapiens 
2022-10-11 | PXD037306 |
ProteomicsAlterations of brain quantitative proteomics profiling revealed the molecular mechanisms of diosgenin against cerebral ischemia reperfusion effects
Diosgenin (DIO), the starting material for the synthesis of steroidal anti-inflammatory drugs in pharmaceutical industry, has been previously demonstrated to display pharmaceutical effects against cerebral ischemic reperfusion (I/R). However, the alterations of brain proteome profiles underlying thi...
ORGANISM(S): Rattus Rattus 
2019-11-18 | PXD016303 |
ProteomicsComparative proteome analyses of Ophiocordyceps sinensis at different stages
In this study, using an iTRAQ quantitative approach coupled with LC-MS/MS and bioinformatics, the proteomes were analyzed for the major three stages covering the fruiting body developmental process, including sclerotium (ST), primordium (PR) and mature fruiting body (MF), with a focus on fruiting bo...
ORGANISM(S): Ophiocordyceps Sinensis 
PXD021260 |
ProteomicsThe differential proteins in dairy cow placental trophoblast cells-derived exosomes between P4 treatment and non P4 treatment
Inadequate fetomaternal interactions could directly lead to pregnancy failure in dairy cows. Exosomes are widely involved in endometrial matrix remodeling, immune function changes, placental development, and other processes of embryo implantation and pregnancy in dairy cows. However, the role of e...
ORGANISM(S): Bos Taurus 
2021-12-21 | PXD030586 |
ProteomicsPredictive Value of Proteomic Markers for Advanced Rectal Cancer with Neoadjuvant Chemoradiotherapy
Thirteen paired pre- and post-nCRT sera from rectal cancer patients were analyzed by isobaric tags for relative and absolute quantitation (iTRAQ) method. Twenty-five proteins were selected for validation by parallel reaction monitoring (PRM) in ninety-one patients.
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032117 |
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