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TranscriptomicsNOT2 proteins promote Pol II-dependent transcription and interact with multiple miRNA biogenesis factors in Arabidopsis
MicroRNAs (miRNAs) play key regulatory roles in numerous developmental and physiological processes in animals and plants. The elaborate mechanism of miRNA biogenesis involves transcription and multiple processing steps. Here, we report the identification of a pair of evolutionarily conserved NOT2_3_...
ORGANISM(S): Arabidopsis thaliana 
2013-01-30 | E-GEOD-42901 | biostudies-arrayexpress
UnknownTranscriptome analysis revealed molecular basis of cold response in Prunus mume.
Not available
S-EPMC10248647 | biostudies-literature
ProteomicsChicken liver TMT-based proteomics
In order to investigate the chicken SLCO1B3 gene functin on the liver metabolism, we used the Yimeng blue eggshell and brown eggshell chickens as the chicken liver SLCO1B3 gene knock-down animal to do the proteomic analysis.
ORGANISM(S): Gallus gallus (Chicken) 
2021-09-09 | PXD022768 | Pride
Chicken Liver Proteome 
ProteomicsAcetylated proteomic identification of stored platelets
In this project, the protein acetylation levels in human platelets and in WT and SIRT3-/- mouse platelets during storage were examined.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-06-09 | PXD026341 | Pride
Stored platelets  acetylation  sirt3 
TranscriptomicsExpression data from Ler and TOP1a-2 inflorescences
DNA topoisomerases release supercoils in DNA introduced during replication or transcription. How DNA topoisomerases impact transcription in the context of eukaryotic chromatin is poorly understood. In this study, using a floral stem cell model in Arabidopsis, we uncovered a role of TOP1a in Polycomb...
ORGANISM(S): Arabidopsis thaliana 
2014-10-14 | E-GEOD-42403 | biostudies-arrayexpress
GenomicsTOP1M-NM-1 functions on nucleosome density
DNA topoisomerases release supercoils in DNA introduced during replication or transcription. How DNA topoisomerases impact transcription in the context of eukaryotic chromatin is poorly understood. In this study, using a floral stem cell model in Arabidopsis, we uncovered a role of TOP1M-NM-1 in Pol...
ORGANISM(S): Arabidopsis thaliana 
2014-10-14 | E-GEOD-53950 | biostudies-arrayexpress
TranscriptomicsOptimized siRNAs with a minimal off-target effect facilitate the screening of essential genes in cancer cells
siRNAs with dN are a promising and easy approach to characterize essential genes by minimizing the off-target effect in cancer cells. mRNA profiles of HCT 116 cells after the transfection of siRNAs or blank control by deep sequencing, using HiSeq 2000
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-62968 | biostudies-arrayexpress
TranscriptomicsPOU2AF1 Functions in the Human Airway Epithelium to Regulate Expression of Host Defense Genes [RNA-Seq]
In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected expression of POU2AF1, a known transcription co-factor previously thought to be expressed only in lymphocytes. Lymphocyte contamination of human ai...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-60989 | biostudies-arrayexpress
UnknownLow plasma serotonin linked to higher nigral iron in Parkinson's disease.
Not available
S-EPMC8692322 | biostudies-literature
UnknownThe Odonata of China: a data-driven, open-access resource for biodiversity research and conservation.
Not available
S-EPMC12724073 | biostudies-literature
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