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TranscriptomicsDC-specific lincRNA controls dendritic cell development and function through interacting with STAT3
To identify the functional non-coding RNAs in human DC development, we explored the gene expression profiles during DC development from peripheral monocytes. Using microarray technique, we identified many annotated lncRNAs with markedly altered expressions during human DC differentiation and maturat...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54143 | biostudies-arrayexpress
TranscriptomicsSmall RNA Solexa sequencing of human liver samples
We applied small RNA Solexa sequencing technology to identify microRNA expression in human liver samples from surgically removed liver tissues including three normal liver tissues (distal normal liver tissue of liver hemangioma), an hepatitis B virus (HBV)-infected liver, a severe chronic hepatitis ...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-21279 | biostudies-arrayexpress
TranscriptomicsRNA Sequencing Analysis of Mouse Bone Marrow Derived Dendritic Cells Transcriptomes During Maturation
Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell maturation. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cell...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-60307 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of dendritic cell Transcriptomes during LPS response
Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cells in RPMI-...
ORGANISM(S): Mus musculus 
2015-09-11 | E-GEOD-69256 | biostudies-arrayexpress
ProteomicsProximity labeling of OsPUX8B.2 interacting proteins with TurboID
Ubiquitin regulatory X (UBX) domain-containing proteins are one of the major subgroups of cofactors of the AAA+ ATPase CDC48/p97 and function in protein quality control involved in diverse cellular processes. However, little is known whether and how the UBX-containing proteins participate in host-mi...
ORGANISM(S): Oryza Sativa 
PXD040074 |
GenomicsConversion of gastric epithelia to endoderm progenitors by small molecules [DNA methylation]
Forced expression of transcription factors for lineage reprogramming brings hope to cell-based therapy. However, its application is hampered by risks of potential genetic aberrations and tumorigenicity. Using defined small molecules in presence of gastric stromal cells as feeders, we reprogramed hum...
ORGANISM(S): Homo sapiens 
2016-07-24 | E-GEOD-69705 | biostudies-arrayexpress
TranscriptomicsGenomic expression analysis of human monocyte-derived DCs and monocytes
To identify the functional non-coding RNAs in human DC development, we explored the gene expression profiles during DC development from peripheral monocytes. Using RNA-seq, we identified many annotated lncRNAs with markedly altered expressions during human DC differentiation and maturation. RNA samp...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54401 | biostudies-arrayexpress
ProteomicsPhosphorylated TLR3 nuclear translocation in cancer cell promotes metastasis and chemoresistance
Phosphorylated TLR3 nuclear translocation in cancer cell promotes metastasis and chemoresistance
ORGANISM(S): Homo Sapiens 
PXD064767 |
ProteomicsMass spectrometry to analyse expressed proteins in Panc1 with or without siRNA silencing PRMT5
Mass spectrometry to analyse expressed proteins in Panc1 with or without siRNA silencing PRMT5
ORGANISM(S): Homo Sapiens 
PXD064762 |
ProteomicsThe effects of enzalutamide on androgen-dependent and androgen-independent prostate cancer cells.
To investigate the mechanisms of drug resistance and castration resistance in prostate cancer, we performed proteomic sequencing on androgen-dependent prostate cancer cells (LNCaP) and androgen-independent cells (AI) treated with enzalutamide.
ORGANISM(S): Homo Sapiens 
2024-11-26 | PXD058261 |
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