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The aim of this project was to investigate the proteins that bind to m6A methylated RN7SK in lung adenocarcinoma A549 cell line. And mass spectrometry of A549 cell treated with or without m6A methylated RN7SK in three replicates.
ORGANISM(S): Homo Sapiens 
The dataset includes the sequencing data of m6A-high and m6A-low LUAD tissues, each of which contains five biological replicates. A total of 3437 protein groups were obtained, 407 differential proteins were obtained . Exerllent repeatability for different biological replicates is indicated based on...
ORGANISM(S): Homo Sapiens 
Lung cancer in Chinese patients has distinct genomic features and lung squamous cell carcinoma (LUSC) has limited biomarkers for targeted therapy even though a lot of progress has been made in genomics research. Systematical research on LUSC at protein level will be beneficial to improve precision m...
ORGANISM(S): Homo Sapiens 
In the era of synthetic biology, design, construction, and utilization of synthetic chromosomes with unique features provide a new strategy to study complex cellular processes such as aging. Herein, we successfully constructed the 884 Kb synXIII of Saccharomyces cerevisiae to investigate replicative...
ORGANISM(S): Saccharomyces Cerevisiae 
2024-10-30 | PXD057330 |
Genomic studies of lung adenocarcinoma (LUAD) have advanced understanding of the disease’s biology and accelerated targeted therapy. However, proteomic characteristics of LUAD remain poorly understood. We carried out comprehensive proteomic analysis of 103 cases of LUAD in Chinese patients. Integrat...
ORGANISM(S): Homo Sapiens 
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