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The complexity and low accessibility of the human brain make it challenging to understand its development, function, and disorders. Brain diseases including neurodegenerative disease and psychiatric diseases incur huge medical and social burdens without effective treatments. While mouse has substant...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-08-12 | PXD034449 | Pride
The complexity and low accessibility of the human brain make it challenging to understand its development, function, and disorders. Brain diseases including neurodegenerative disease and psychiatric diseases incur huge medical and social burdens without effective treatments. While mouse has substant...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-08-12 | PXD033420 | Pride
Porcine epidemic diarrhea virus (PEDV) has reemerged as the main pathogen of piglets due to its high mutation feature. Monolaurin (ML) is a natural compound with a wide range of antibacterial and antiviral activities. However, the role of ML in PEDV infection is still unknown. This study aimed to ev...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-16 | PXD029561 | Pride
Approximately 35 million people worldwide suffer from Alzheimer’s disease (AD). Existing therapeutics, while moderately effective, are currently unable to stem the widespread rise in AD prevalence. AD is associated with an increase in amyloid beta (A) oligomers and hyperphosphorylated tau, along wit...
ORGANISM(S): Mus musculus 
Several versions of SWI/SNF complexes, BAF and PBAF, have been described based on unique subunit composition. We find that T cell development in the thymus and lymphoid periphery is largely normal in the absence of the PBAF-specific component BAF180. However, BAF180-deficient Th2 cells express high...
ORGANISM(S): Mus musculus 
The central nervous system normally functions at O2 levels which would be regarded as hypoxic by most other tissues. However, most in vitro studies of neurons and astrocytes are conducted under hyperoxic conditions without consideration of O2-dependent cellular adaptation. We analyzed the reactivi...
ORGANISM(S): Rattus norvegicus 
Comparison of various ovarian tumors and ovarian cell lines. Keywords: Various ovarian tumors and cell lines. Samples from ovarian tumors and ovarian cell lines were examined for their microRNA expression patterns.
ORGANISM(S): Homo sapiens 
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