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ProteomicsTandem Mass Tag based quantitative proteomic analysis of colorectal cancer cell lines
Overexpression of Oxysterol-Binding Protein-Related Protein 3 (ORP3) in colorectal cancer cell lines
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD074308 | Pride
GenomicsNext-generation sequencing of targeted loci modified by SMART editing
HEK293T/17 cells were genetically edited by SMART editing to assess the effectiveness of SMART editing. There are 4 target genes: CXCR4, Lmnb1, Nrl and NRXN3. Cultured cells were first synchronized at the G2/M phase. Then, cells were transfected with Cas9 RNP along with SMART or traditional template...
ORGANISM(S): Homo sapiens 
2025-04-21 | E-MTAB-14909 | biostudies-arrayexpress
ProteomicsBiotin-pgRNAWT or Biotin-pgRNAAUUUA to AUCUC RNA pulldown LC-MS/MS
The nuclear export of HBV RNAs allows the virus to synthesize its proteins through the translation machinery and replicate its genome through reverse transcription in the cytoplasm. However, the molecular mechanisms underlying this important process remain largely obscure. To illustrate this process...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD044015 | Pride
Rna nuclear export Pgrna binding proteins Rna stability Au rich element Hbv rna 
ProteomicsDIA proteomic profiling of dorsal skin from Dendrobium officinale polysaccharide-treated C57BL/6 mice
This project contains DIA-PASEF proteomics data generated from dorsal skin tissues of male C57BL/6 mice in a control group, a DHT-induced androgenetic alopecia (AGA) model group, and a Dendrobium officinale polysaccharide (DOP, 7.5 mg/mL)-treated group. The study was designed to investigate proteomi...
ORGANISM(S): Mus Musculus 
2026-04-20 | PXD077413 |
ProteomicsIntegrated Optoproteomics and AP-MS Reveals interactome Remodeling Upon NLRP3 Inflammasome Activation
NOD-like receptor family pyrin domain-containing 3 (NLRP3) is a critical intracellular danger sensor that forms inflammasome complexes to drive inflammatory caspase activation; however, the components and dynamic organization of the NLRP3 inflammasome remain incompletely defined. Here, we systematic...
ORGANISM(S): Mus Musculus 
2026-06-11 | PXD079555 |
MetabolomicsGNPS - Serum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | GNPS
MetabolomicsExploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors.

The gut microbiome has emerged as a potential factor in cancer pathogenesis, but its role in non-functioning pituitary neuroendocrine tumors (NF-PitNETs) remains unclear. This study aimed to elucidate gut microbiome and metabolomic alterations in NF-PitNETs by comparing microbial diversity, patho...

2025-06-16 | MTBLS12328 | MetaboLights
ProteomicsA proximity labeling map of SARS-CoV-2 and human
The global epidemic caused by the coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted in the infection of over 200 million people. To extend the knowledge of interactions between SARS-CoV-2 and humans, we systematically investigate the interactome of 29 viral protei...
ORGANISM(S): Homo Sapiens 
2022-01-06 | PXD022086 |
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
ProteomicsHistone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
To look for factors that may have preferential binding to H3S28ph and mediate the stimulation to gene expression.
ORGANISM(S): Mus Musculus 
2022-05-25 | PXD034125 |
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