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ProteomicsExpedited mapping of the ligandable proteome using fully functionalized enantiomeric probe pairs
A fundamental challenge in chemical biology and medicine is to understand and expand the fraction of the human proteome that can be targeted by small molecules. We recently described a strategy that integrates fragment-based ligand discovery with chemical proteomics to furnish global portraits of re...
ORGANISM(S): Homo sapiens (Human) 
2019-10-29 | PXD015104 | Pride
Human Pbmcs Hek293t Lc-ms/ms 
MetabolomicsThe lipid-metabolism enzyme ECI2 reduces neutrophil extracellular traps formation for colorectal cancer suppression
Abnormalities in ether lipid metabolism as well as the formation of neutrophil extracellular traps have recently been recognized as detrimental factors affecting tumorigenesis and progression. However, the role of abnormal ether lipid metabolism in colorectal cancer (CRC) evolution has not been repo...
2024-10-01 | MTBLS10323 | MetaboLights
ProteomicsiTRAQ quantitative analysis for AIS study
Relative quantitative analysis was performed to compare the proteomic profiles in plasma samples between healthy control and AIS subjects with different risk of curve progression.
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023915 | Pride
Ais Plasma Itraq 
OtherThe Tissue-Based Proteogenomics Reveals that Human Testis Endows Plentiful Missing Proteins.
Data from ProteomeXchange, PXD ID: PXD002179. Experiment: CHPP_TESTIS_Tricine, file: CHPP_TESTIS_Tricine_2017.mgf. Published as part of J Proteome Res. 2015 . From the Abstract: {{i}} Investigations of missing proteins (MPs) are being endorsed by many bioanalytical strategies. We proposed that prot...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310023526 | GPMDB
Resource Reanalysis 
UnknownBrkAutoDisplay: functional display of multiple exogenous proteins on the surface of Escherichia coli by using BrkA autotransporter.
Not available
S-EPMC4558763 | biostudies-literature
ProteomicsHs_C-HPP_Testis_Regular-SDS-PAGE
CN-CHPP 2015 Testis, Regular-SDS-PAGE
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005356 | PeptideAtlas
ProteomicsHs_C-HPP_Testis_Tricine-SDS-PAGE
CN-CHPP 2015 Testis, Tricine-SDS-PAGE
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005333 | PeptideAtlas
TranscriptomicsGlobal analysis of metastasis-associated gene expression in the primary cultures from clinical specimens of ccRCC
Metastatic clear cell renal cell carcinoma (ccRCC) has a poor prognosis and unpredictable course and there are no molecular markers that reliably predict ccRCC metastasis. In this study, specimens from 84 patients with ccRCC were directly cultured in vitro. The primary cultures from 38 of 94 specime...
ORGANISM(S): Homo sapiens 
2008-08-27 | E-GEOD-11072 | biostudies-arrayexpress
ProteomicsCN-CHPP 2015 Testis Project
The testis tissue-based trans-omics was a feasible approach to find more missing proteins (MPs) because it was reported higher gene expression found in testis tissues. Three testis tissues and two protein separation strategies were selected to quantitatively evaluate gene expression abundance at the...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-06-26 | MSV000082510 | MassIVE
ProteomicsMiRNA-378a-5p attenuates the development of abdominal aortic aneurysm via ABLIM1-MKL1 signaling pathways
Abstract Objectives: Abdominal aortic aneurysm (AAA) is a fatal cardiovascular disease with no effective drug treatment currently available. The aberrant expressions of microRNAs (miRNAs) contribute to AAA pathogenesis. In this study, we aimed to perform miRNA microarray analysis to screen for diffe...
ORGANISM(S): Homo Sapiens 
2026-01-13 | PXD073033 |
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