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This dataset contains multi-omics and neurobiological data from a study demonstrating that xylitol ameliorates ASD-like phenotypes in mutant mice via the gut-brain axis. It includes gut microbiota (16S) and targeted metabolomics data showing restoration of microbial and neurotransmitter balance, alo...
ORGANISM(S): Mus Musculus 
2025-12-08 | PXD071711 |
This project aims to elucidate the molecular mechanisms by which the gut microbial metabolite β-guanidinopropionic acid (β-GPA) alleviates hyperlipidemic periodontitis (HPD). We performed Tandem Mass Tag (TMT) based quantitative proteomic analysis on periodontal tissues from HPD model mice versus th...
ORGANISM(S): Mus Musculus 
Functional crosstalk between histone modifications and chromatin remodeling has emerged as a key regulatory mode of transcriptional control during drug resistance, but the underlying mechanisms are not fully understood. Here we demonstrate that different proteins and their acetylation modification r...
ORGANISM(S): Homo Sapiens 
2023-02-20 | PXD040298 |
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