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Background: Blocking glycolysis inhibits regulatory T cells (Tregs), which are often hijacked by tumor cells whose survival relies on glycolysis to inhibit antitumor immunity. However, how glycolysis influences Treg proliferation/differentiation remains unclear. Monocarboxylate transporters (MCTs...

2024-08-06 | MTBLS8002 | MetaboLights
Lipid nanoparticles (LNPs) are widely used for nucleic acid delivery but face challenges like limited targeting and accelerated blood clearance. We design three ionizable oligo-mers (IOs) that, with PLA-PEG, form Ionizable Polymeric Micelles (IPMs), a potential siRNA delivery system, which can achie...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-21 | PXD057444 | Pride
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
In order to investigate the protein expression of S. intermedius under high temperature stress. The study was conducted with the high-temperature resistant strain of S. intermedius and the control group of S. intermedius.
ORGANISM(S): Strongylocentrotus Intermedius 
2023-07-18 | PXD043884 |
Palytoxin (PLTX) is a polyether Marine toxin isolated from sea anemones. It is one of the most toxic non-protein substances, causing many people to be poisoned every year and die in severe cases. With its known impact on Na+, K+-ATPase, much still remain unclear about the mechanism of PLTX action. H...
ORGANISM(S): Homo Sapiens 
2022-03-24 | PXD032777 |
we collected Prepared Daqu samples from 6 different production cycles of the Kweichow Moutai Liquor and characterized their microbial community and function by label-free quantitative metaproteomic methods.
ORGANISM(S): Enterococcus Faecalis 
2022-08-03 | PXD035791 |
OGT, the only facilitator which attaches the monosaccharide to many oncogenic factors or tumor suppressors, has been suggested to play an influential role in tumorigenesis and metastasis of HCC. OGT interactome analyses indicates that disordered OGT may serve as a hub protein to activate the buildin...
ORGANISM(S): Homo Sapiens 
2023-01-12 | PXD039365 |
Phosphorylation sites identified at the C-terminus of mGlu5 by mass spectrometry analysis
ORGANISM(S): Homo Sapiens 
2026-04-01 | PXD076479 |
Chloroplast Nanotechnology for General Health using Omics analysis
ORGANISM(S): Spinacia Oleracea 
2026-03-21 | PXD076001 |
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