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ProteomicsPlant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages
A growing body of evidence supports the importance of T cell responses to protect against severe influenza, promote viral clearance and ensure long-term immunity. Plant-derived virus-like particle (VLP) vaccines bearing influenza hemagglutinin (HA) have been shown to elicit strong humoral and CD4+ T...
ORGANISM(S): Homo sapiens (Human) 
2019-05-28 | PXD010519 | Pride
Influenza Cell-mediated immunity Cross-presentation Major histocompatibility complex class i Human monocyte-derived macrophage High-resolution mass spectrometry Plant-derived vaccine Virus-like particle 
TranscriptomicsThe physicochemistry of capped nanosilver predicts it biological activity in brain endothelial (RBEC4) cells
This study uses the RBEC4 cell model to examine if nanosilver of different sizes (10nm and 75nm) and cappings (citrate and polyvinylpyrrolidone(PVP)) affect its cellular permeability and genomic response. RBEC4 cells (95% confluent) were screeened for changes in gene expression after 18 hour exposur...
ORGANISM(S): Rattus norvegicus 
2013-05-31 | E-GEOD-47543 | biostudies-arrayexpress
ModelsLee2009 - Adaptive immune response to Influenza A Virus infection
No description
2014-09-15 | MODEL1406230000 | BioModels
TranscriptomicsThe Cellular and Genomic Response of  Dopaminergic Neurons (N27) to Commericial “Capped” Nanosilver
Global gene expression indicated that N27 neurons exposed to each nanoAg material (1.0 ppm, 18 hr) responded primarily to PVP coated nanoAg of both sizes with affected pathways largely associated with mitochondrial dysfunction (PVP 75 nm nanoAg) and Nrf-2 mediated oxidative stress (PVP 10 nm nanoAg)...
ORGANISM(S): Rattus norvegicus 
2013-06-20 | E-GEOD-48087 | biostudies-arrayexpress
TranscriptomicsTumorigenic carryover effects of early life exposure to dichloroacetic acid in male B6C3F1 mice
Here we investigated the longterm carryover effects of dichloroacetic acid (DCA), a common by-product of drinking water chlorination, on hepatic tumorigenesis in mice. Our findings demonstrate that postnatal exposure to a common drinking water contaminant results in longterm carryover effects on tum...
ORGANISM(S): Mus musculus 
2015-02-26 | E-GEOD-58585 | biostudies-arrayexpress
UnknownElective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.
Not available
S-EPMC8189635 | biostudies-literature
UnknownCost-Effectiveness of Treatments after Closed Extraarticular Distal Radius Fractures in Older Adults from the WRIST Clinical Trial.
Not available
S-EPMC7855198 | biostudies-literature
UnknownImpact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures
Not available
S-EPMC8410470 | biostudies-literature
UnknownGenomic architecture of autism from comprehensive whole-genome sequence annotation.
Not available
S-EPMC10726699 | biostudies-literature
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
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