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TranscriptomicsTranscription profiling of Arabidopsis after induction of Golden2-like (GLK1 or GLK2) expression in a glk mutant background to identify downstream gene targets
Defining the transcriptome response to the brief induction of Golden2-like (GLK) gene expression in a glk mutant background. Expression of either GLK1 or GLK2 from an inducible promoter by the application of dexamethasone. Changes to transcriptome four hours after induction are compared with uninduc...
ORGANISM(S): Arabidopsis thaliana 
2009-02-01 | E-MEXP-1794 | biostudies-arrayexpress
ProteomicsVCP D1 ATPase activation enhances both autophagic and proteasomal neurotoxic protein clearance
Autophagy upregulation enhances the clearance of various neurotoxic proteins and ameliorates their toxicities in disease models. Thus, autophagy activators may have therapeutic utility. Here, we have identified the essential protein VCP/p97 as a target of the autophagy-inducing molecule SMER28, prov...
ORGANISM(S): Escherichia coli 
2022-07-15 | PXD027750 | Pride
Beclin 1 Atpase Smer28 Autophagy Ubiquitin-proteasome system Limited proteolysis Lip-ms Neurodegeneration Vcp Protein quality control 
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