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UnknownInhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI.
Not available
S-EPMC6269309 | biostudies-literature
ProteomicsMeCP2 requires interactions with nucleosome linker DNA to read chromatin DNA methylation
ethyl-CpG-binding protein 2 (MeCP2) is an epigenetic reader essential for neuronal function, but how it binds DNA methylation within chromatin is still unclear. Using designer nucleosomes we observe that MeCP2 preferentially binds DNA methylation positioned at multiple sites around the nucleosome. S...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD064826 | Pride
Mecp2 Cross-linking mass spectrometry Dna methylation Nucleosomes Chromatin 
ProteomicsThe interaction between DNMT3A with H3Kc36me2 modified nucleosomes
DNA methyltransferase 3A (DNMT3A) plays a critical role in establishing and maintaining DNA methylation patterns, essential for the dynamic organization of vertebrate genomes. However, the mechanisms underlying DNMT3A1's recruitment and function within different chromatin environments remain unclear...
ORGANISM(S): Homo sapiens (Human) 
2024-12-07 | PXD046529 | Pride
Dnmt3a Crosslink Nucleosomes 
UnknownA specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients.
Not available
S-EPMC8262329 | biostudies-literature
UnknownFactors predicting conversion from colon capsule endoscopy to conventional optical endoscopy-findings from the CESCAIL study.
Not available
S-EPMC12070752 | biostudies-literature
UnknownThe N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment.
Not available
S-EPMC11624362 | biostudies-literature
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownCampath, calcineurin inhibitor reduction and chronic allograft nephropathy (3C) study: background, rationale, and study protocol.
Not available
S-EPMC3674985 | biostudies-literature
UnknownGenetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Not available
S-EPMC3431328 | biostudies-literature
UnknownDevelopment and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Not available
S-EPMC5408574 | biostudies-literature
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