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ProteomicsImmunopeptidomics-based design of highly effective mRNA vaccine formulations against Listeria monocytogenes
Listeria monocytogenes is a foodborne intracellular bacterial pathogen leading to human listeriosis. Despite a high mortality rate and increasing antibiotic resistance no clinically approved vaccine against Listeria is available. To identify antigens for this bacterial pathogen that can be encoded i...
ORGANISM(S): Homo sapiens (Human) Listeria monocytogenes EGD 
2022-09-26 | PXD031451 | Pride
Tmt Fusion lumos Listeria monocytogenes Hela Immunopeptidomics Epitope discovery Bacterial infection Label-free Q exactive hf Hct-116 Antigen discovery Vaccine development 
UnknownCD90-targeted lentiviral vectors for HSC gene therapy.
Not available
S-EPMC10556220 | biostudies-literature
ProteomicsBenchmarking CHIMERYS using Wide Window Acquisition and Classical Narrow Isolation Window Data Dependent Acquisition
A comprehensive proteome map is essential to elucidate molecular pathways and protein functions. Although great improvements in sample preparation, instrumentation and data analysis already yield-ed impressive results, current studies suffer from a limited proteomic depth and dynamic range there-for...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2024-02-13 | PXD045500 | Pride
E. coli Wide window acquisition Yeast Direct injection Micropillar array chromatography Vanquish neo Hela Orbitrap exploris 480 Single cells Trap-and-elute 
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