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TranscriptomicsLoss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [NSC34]
Aims: Loss of nuclear TDP-43 characterises sporadic and most familial forms of amyotrophic lateral sclerosis (ALS). TDP-43 (encoded by TARDBP) has multiple roles in RNA processing. We aimed to determine whether 1) RNA splicing dysregulation is present in lower motor neurons in ALS and in a motor neu...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-56503 | biostudies-arrayexpress
TranscriptomicsProtein profiling reveals five principal chromatin types in Drosophila cells
The local protein composition of chromatin is important for the regulation of transcription and other functions. By integrative analysis of genome-wide binding maps of 53 broadly selected chromatin components in Drosophila cells, we show that the genome is segmented into five principal chromatin typ...
ORGANISM(S): Drosophila melanogaster 
2010-10-01 | E-GEOD-22069 | biostudies-arrayexpress
TranscriptomicsLoss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [LCM]
Aims: Loss of nuclear TDP-43 characterises sporadic and most familial forms of amyotrophic lateral sclerosis (ALS). TDP-43 (encoded by TARDBP) has multiple roles in RNA processing. We aimed to determine whether 1) RNA splicing dysregulation is present in lower motor neurons in ALS and in a motor neu...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-56500 | biostudies-arrayexpress
UnknownPrognostic factors for predicting outcomes after intramedullary nailing of the tibia.
Not available
S-EPMC3448300 | biostudies-literature
UnknownSNAPSHOT USA 2020: A second coordinated national camera trap survey of the United States during the COVID-19 pandemic.
Not available
S-EPMC9347782 | biostudies-literature
UnknownRandomized trial of reamed and unreamed intramedullary nailing of tibial shaft fractures.
Not available
S-EPMC2663330 | biostudies-literature
UnknownCharacter, Incidence, and Predictors of Knee Pain and Activity After Infrapatellar Intramedullary Nailing of an Isolated Tibia Fracture.
Not available
S-EPMC4761290 | biostudies-literature
UnknownMammal responses to global changes in human activity vary by trophic group and landscape.
Not available
S-EPMC11090811 | biostudies-literature
UnknownDevelopment and validation of an instrument to predict functional recovery in tibial fracture patients: the Somatic Pre-Occupation and Coping (SPOC) questionnaire.
Not available
S-EPMC3263327 | biostudies-literature
UnknownUse of both Short Musculoskeletal Function Assessment questionnaire and Short Form-36 among tibial-fracture patients was redundant.
Not available
S-EPMC2782578 | biostudies-literature
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