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Unknown3CAPS - a structural AP-site analogue as a tool to investigate DNA base excision repair.
Not available
S-EPMC4797279 | biostudies-literature
TranscriptomicsMixed Culture Gene Expression of E. coli and Pseudomonas aeruginosa grown on defined media with N-acetyl glucosamine
Transcriptional profiles of Escherichia coli MG1655 in mixed culture with Pseudomonas aeruginosa PAO1 showed a number of E. coli genes to be upregulated including purA-F and other genes associated with purine synthesis. In contrast, genes associated with pyrimidine synthesis were unaffected. Competi...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-11-29 | E-GEOD-26932 | biostudies-arrayexpress
TranscriptomicsRNA-Seq: Aeroplysinin-1 on gene expression in primary human lung endothelial cells with and without influenza A
Uninfected and influenza (H1N1, x31) conditions were investigated. Three biological replicates were used per group for RNASeq analysis. A non functional derivative of Aeroplysinin-1 was also tested (Ap1) at the same concentration and time point. Samples had an Agilent Bioanalyzer RNA integrity num...
ORGANISM(S): Homo sapiens 
2025-06-14 | E-MTAB-15177 | biostudies-arrayexpress
TranscriptomicsEssential Role of Thioredoxin and Glutathione in Pancreas
Acute pancreatitis (AP) is defined by acute inflammatory injury to the pancreas and oxidative stress has been implicated as a mechanistic driver of disease progression. To delineate the contribution of reactive oxygen species (ROS) detoxification pathways in AP, we employed a genetic model of pancre...
ORGANISM(S): Mus musculus 
2025-08-30 | E-MTAB-15511 | biostudies-arrayexpress
TranscriptomicsA putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs
Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs. An experimental purification in which a presumed RNA binding protein was used for an RNA immunoprecipitation and microarray analysis (RIP-CHIP). Total cell extracts w...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-16942 | biostudies-arrayexpress
TranscriptomicsMixed Culture Gene Expression of E. coli and Pseudomonas aeruginosa
Transcriptional profiles of Escherichia coli MG1655 in mixed culture with Pseudomonas aeruginosa PAO1 showed a number of E. coli genes to be upregulated including purA-F and other genes associated with purine synthesis. In contrast, genes associated with pyrimidine synthesis were unaffected. Competi...
ORGANISM(S): Escherichia coli 
2011-11-09 | E-GEOD-26931 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human type 2 diabetes patients to screen for genes differentially methylated in T2DM MeDIP ARRAY_NGT_vs_T2DM
Here, we performed a genome-wide promoter analysis of DNA methylation to screen for genes differentially methylated in T2DM.
We used methylated DNA immunoprecipitation (MeDIP), combined with microarray technology (Keshet et al., 2006; Weber et al., 2005), to discover whether changes in DNA methyl...
ORGANISM(S): Homo sapiens 
2010-07-15 | E-MEXP-2253 | biostudies-arrayexpress
UnknownRecessive loss-of-function mutations in AP4S1 cause mild fever-sensitive seizures, developmental delay and spastic paraplegia through loss of AP-4 complex assembly.
Not available
S-EPMC4380070 | biostudies-literature
ProteomicsShotgun Proteomics of BN-PAGE-Resolved Chloroplasts
Blue Native-PAGE resolves protein complexes in their native state. When coupled with immunoblotting, it can be used to identify the presence of high molecular weight complexes at high resolution for any protein, given a suitable antibody. To identify proteins in high molecular weight complexes on a ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-12-23 | PXD003162 | Pride
Oligomeric state Native gel Protein complex Native molecular weight Chloroplast 
GenomicsGenome-wide occupancies of multiple transcription activators in PDLSCs induced by GIPRA
Our previous study (Environ Pollut. 2023;323:121307) has indicated that Glucose-dependent insulinotropic polypeptide receptor (GIPR) is down-regulated in periodontal ligament stem cells (PDLSCs) by cigarette and E-cig. In the current study, ChIP-seq was conducted to study the genome-wide occupancies...
ORGANISM(S): Homo sapiens 
2025-08-06 | E-MTAB-15381 | biostudies-arrayexpress
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