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TranscriptomicsMetabolic and Transcriptional Reprogramming in Developing Soybean (Glycine max) Embryos
Soybean (Glycine max) seeds are an important source of seed storage compounds, including protein, oil, and sugar used for food, feed, chemical, and biofuel production. We assessed detailed temporal transcriptional and metabolic changes in developing soybean embryos to gain a systems biology view of ...
ORGANISM(S): Glycine max 
2013-12-13 | E-GEOD-46153 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse striatum from 12 weeks-old R6/2 vs. control animals
This SuperSeries is composed of the following subset Series:; GSE9803: Striatal gene expression data from 12 weeks-old R6/2 mice and control mice (set 1); GSE9804: Striatal gene expression data from 12 weeks-old R6/2 mice and control mice (set 2) Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9857 | biostudies-arrayexpress
TranscriptomicsInvestigation of placental DNA methylation in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2018-11-01 | E-MTAB-6421 | biostudies-arrayexpress
ProteomicsHepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk
Individuals with hepatic steatosis often display several metabolic abnormalities including insulin resistance and muscle atrophy. Previously, we found that hepatic steatosis results in an altered hepatokine secretion profile, thereby inducing skeletal muscle insulin resistance via inter-organ crosst...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD027332 | Pride
Insulin resistance Metabolism Muscle atrophy Liver steatosis Nafld Inter-organ crosstalk 
UnknownFarnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice.
Not available
S-EPMC9392365 | biostudies-literature
TranscriptomicsInvestigation of placental gene expression in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2019-01-31 | E-MTAB-6418 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of murine mammary glands to study early events occuring in p53-independent hormone-induced tumorigenesis
LH-overexpressing mice display elevated levels of mammogenic hormones and consequently develop spontaneous mammary tumors with a median latency of 41 weeks. Tumors occur in the absence of p53 mutations and in the presence of a seemingly functional p53 signaling pathway. At 16 weeks of age, no histol...
ORGANISM(S): Mus musculus 
2007-09-11 | E-GEOD-3348 | biostudies-arrayexpress
UnknownMaintenance of Remission with Partial Enteral Nutrition Therapy in Pediatric Crohn's Disease: A Retrospective Study.
Not available
S-EPMC5439067 | biostudies-literature
TranscriptomicsTranscription profiling of striatum from 12 weeks-old R6/2 mice and control mice (set 2)
To test the hypotheses that mutant huntingtin protein length and wild-type huntingtin dosage have important effects on disease-related transcriptional dysfunction, we compared the changes in mRNA in seven genetic mouse models of Huntington's disease (HD) and postmortem human HD caudate. Transgenic m...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9804 | biostudies-arrayexpress
UnknownCardiopulmonary Exercise Testing in Childhood in Late Preterms: Comparison to Early Preterms and Term-Born Controls.
Not available
S-EPMC9605114 | biostudies-literature
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