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MetabolomicsGut Microbiome and Serum Metabolic Alterations in Recurrent Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is a common complication of pregnancy, particularly affecting multiparous women with a history of GDM, who face a recurrence risk approaching 50%. This study investigates the association between gut microbiota modifications and metabolic profiles from early to ...

2025-07-21 | MTBLS12326 | MetaboLights
ProteomicsProteomic analysis of hydrolase levels in the lysosomes from macrophages stimulated with or without LPS via LC_MS
Proteomic analysis of hydrolase levels in the lysosomes from macrophages stimulated with or without LPS via liquid chromatography–mass spectrometry (LC-MS), highlighting the expected LPS-induced increase in accumulation of proteases, ribonucleases (RNase) and other hydrolases.
ORGANISM(S): Mus Musculus 
PXD056776 |
ProteomicsDegradation analysis of SARS-CoV-2 proteins after incubation with h-lysoTRAP based on the proteomics data
To investigate the degradation activity of proteases inside lysosomal "TRAP", we conducted proteomic analysis of lysosomal "TRAP" with trapped authentic SARS-CoV-2.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD056801 |
ProteomicsDetection of residual peptides of SARS-CoV-2 peptide after a 24-hour co-incubation with h-lysoTRAP via proteomic analysis
To gain a deeper insight into the residual SARS-CoV-2 peptides after degradation, we directly detected fragments (lower than 10 (kilodalton) kDa) of degraded SARS-CoV-2 via LC-MS, and overlapped these with the 3D crystal structure of SARS-CoV-2 proteins.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD056987 |
ProteomicsDegradation analysis of SARS-CoV-2 proteins by h-lysoTRAP
To investigate the degradation activity of proteases inside lysosomal "TRAP", we conducted proteomic analysis of lysosomal "TRAP" with trapped authentic SARS-CoV-2.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD056985 |
TranscriptomicsIdentifying microRNA-mRNA regulatory networks in colorectal cancer by a combination of expression profile and bioinformatics analysis
A multi-step approach combining microarray profile and bioinformatics analysis was adopted to identify the CRC specific miRNA-mRNA regulatory network. First, differentially expressed miRNAs and mRNAs were found out in CRC samples compared with normal epithelial tissues by miRNA and mRNA microarray r...
ORGANISM(S): Homo sapiens 
2013-01-03 | E-GEOD-35982 | biostudies-arrayexpress
Proteomicsone step carboxyl group isotopic labeling for quantitative analysis of N-glycopeptide by Mass Spectrometry
Glycosylation is one of the most common and important post-translational modifications. Quantitative analysis of intact N-glycopeptides is critical to understand the role of protein glycosylation in physiological and pathological processes. In this work, we developed a novel approach called methylam...
ORGANISM(S): Homo Sapiens 
PXD021104 |
ProteomicsProteomics analysis of glioma cells and astrocytes
Cell membranes harvested from U251 and primary healthy astrocytes were prepared for LC-MS/MS analysis. After analysis, we could obtain a pool of proteins, which were enriched in the U251 cell membrane sample rather than healthy astrocyte membrane sample.
ORGANISM(S): Homo Sapiens 
2022-01-06 | PXD030760 |
ProteomicsProteomics dataset of COVID-19 and control patients
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
PXD029023 |
ProteomicsLysine-targeting, covalent inhibitors of bromodomain BD1 of BET proteins in live cells and animals
We report herein a set of activity-based probes (ABPs; P3-P7) based on various lysine-reactive covalent warheads capable of global profiling of ligandable lysine within BRDs in live cells and animals. Chemoproteomic experiments with P7 by utilizing 2-ethynylbenzaldehyde (EBA) identified 18 endogenou...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD058513 |
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