Sort   by:  
 Page size 
TranscriptomicsDistinct gene expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection
Analysis of global gene expression profiles of flow cytometry-sorted, different pathogen-specific CD4+ T cell populations from the same peripheral blood mononuclear cells (PBMC), to identify molecular parameters that regulate differential susceptibilities of these CD4+ T cells to HIV infection. The ...
ORGANISM(S): Homo sapiens 
2012-12-13 | E-GEOD-42853 | biostudies-arrayexpress
ProteomicsBlood and Urine-Based Liquid Biopsy for early stage cancer investigation: Taken Clear Renal Cell Carcinoma as A Model
We analyzed samples of tumor tissue, plasma, and urine from a cohort of 27 ccRCC patients with T1-2 stage and 27 matched healthy controls, using liquid chromatography–mass spectrometry (LC-MS) for proteomic analysis. We integrated the differential proteins found in the three types of samples to expl...
ORGANISM(S): Homo Sapiens 
PXD043118 |
ProteomicsMass spectrometric analysis of fluorophore labeled albumins
A genetic engineering strategy for editing near-infrared-II fluorophores. The labeled albumin proteins were digested using suspension trapping (STrap) approach with in-house packed glass fiber filters. The LC-MS/MS analysis was performed on a nanoLC-Q Exactive MS system. The protein identification w...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-07 | MSV000087386 | MassIVE
ProteomicsUrinary proteome and metabolome uncover tumor microenvironment and cellular metabolism changes of renal clear cell carcinoma
We applied LC-MS to profile the urine proteome and metabolome of 314 ccRCC, 341 healthy control and 49 kidney benign disease enrolled from three cohorts to a great depth. Functionally, we revealed significant changes of extracellular matrix (ECM) organization, complement and coagulation cascades, am...
ORGANISM(S): Homo Sapiens 
PXD064183 |
ProteomicsProteomic profiling and tumor microenvironment characterization reveal molecular and immunological hallmarks of left-sided and right-sided colon cancer tumorigenesis
The protein landscapes of LSCC and RSCC were constructed, and the hallmarks of tumorigenesis and characteristics of TME for LSCC and RSCC were identified. These findings improved our understanding of LSCC and RSCC and may facilitate the development of diagnostic or therapeutic targets for LSCC and R...
ORGANISM(S): Homo Sapiens 
PXD042962 |
ProteomicsXAF1 promotes the innate immune response against RNA viruses by regulating chromatin accessibility
The raw data of mass spectrometry in this article including MAVS-Turbo ID, XAF1 phosphorylation site and XAF1 interacting protein in nuclear
ORGANISM(S): Homo Sapiens 
2022-12-05 | PXD038540 |
ProteomicsTargeting mitochondria-inflammation circuit by β-hydroxybutyrate mitigates heart failure with preserved ejection fraction
Rationale: Over 50% of heart failure patients have preserved, rather than reduced ejection fraction (HFpEF vs. HFrEF). Complexity of its pathophysiology and the lack of animal models hamper the development of effective therapy for HFpEF. Objective: This study was designed to investigate the metabol...
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD021957 |
ProteomicsSARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of the ongoing global pandemic of coronavirus disease 2019 (COVID-19). Loss of smell and taste are new identified symptoms of COVID‐19, and both of these are related to cilia dysfunction. However, the pathological me...
ORGANISM(S): Homo Sapiens 
2022-02-23 | PXD031842 |
Sort   by:  
 Page size