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Mice were i.p. injected Thiamet G (TG) or saline, and mouse brain cortex tissues were analyzed for O-GlcNAc by LC-MS/MS with TMT based quantification. Data was searched with MS-GF+ using PNNL's DMS processing pipeline.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
To understand how Lon protease 1(Lonp1) knockin promotes prostate cancer metastasis in vivo, we performed proteomic analysis on prostates extracted from 40-week-old wild-type (WT), Lonp1KI, Pten-/- and Pten-/-; Lonp1KI mice.
ORGANISM(S): Mus Musculus 
2024-06-12 | PXD053059 |
To address how Mbd5 binding to m5C RNAs mediates transcriptional activation of its target genes. Using the Tg[zhsp70l:FLAGmbd5iso2-E2AGFP] zebrafish, we performed heat shock at multiple developmental stages and carried out co-immunoprecipitation (co-IP) at 4 dpf using the FLAG antibody, followed by ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2024-06-16 | PXD048128 | Pride
Whole transcriptome sequencing (RNA-seq) was performed on 39 PC specimens. Among them, 21 specimens also had WES data.
Whole-exome sequencing (WES) was performed on a total of 34 PC specimens, with 15 cases having matched gDNAs extracted from blood.
Peritoneal carcinomatosis (PC) occurs frequently in gastric adenocarcinoma (GAC) patients and confers poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC’s development/progression remain largely unknown. Here we characterized exome/transcriptome/immune...
Data Access Committee EGAC00001001026
Phenotypic plasticity has emerged as an important mechanism of therapy resistance in cancers, yet the underlying molecular mechanisms remain unclear. Using an established breast cancer cellular model for endocrine resistance, we show that hormone resistance is associated with enhanced phenotypic pla...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-24 | MSV000083857 | MassIVE
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